POSTN

Gene Symbol	POSTN
Entrez Gene	10631
Alt Symbol	OSF-2, OSF2, PDLPOSTN, PN, periostin
Species	Human
Gene Type	protein-coding
Description	periostin, osteoblast specific factor
Other Description	osteoblast specific factor 2 (fasciclin I-like)\|periodontal ligament-specific periostin\|periostin
Swissprots	Q5VSY5 Q15064 C0IMJ4 C0IMJ1 B1ALD8 Q8IZF9 Q15063 F5H628 D2KRH7 Q3KPJ5 Q29XZ0 C0IMJ2
Accessions	EAX08590 EAX08591 EAX08592 EAX08593 EAX08594 Q15063 AI580215 AK021444 AK297914 BAH12690 AK300261 BAH13247 AK304640 BAG65419 AY140646 AAN17733 AY918092 AAY15840 BC106709 AAI06710 BC106710 AAI06711 BG938993 BP335818 BQ575951 BY795054 D13665 BAA02836 D13666 BAA02837 DC403736 EU262883 ABY86630 EU262884 ABY86631 EU262885 ABY86632 EU262886 ABY86633 GU354210 ADA79517 XM_005266231 XP_005266288 XM_005266232 XP_005266289 NM_001135934 NP_001129406 NM_001135935 NP_001129407 NM_001135936 NP_001129408 NM_001286665 NP_001273594 NM_001286666 NP_001273595 NM_001286667 NP_001273596 NM_006475 NP_006466
Function	Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX (By similarity). Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization. {ECO:0000250, ECO:0000269\|PubMed:12235007, ECO:0000269\|PubMed:18450759}.
Subcellular Location	Golgi apparatus {ECO:0000250}. Secreted, extracellular space, extracellular matrix {ECO:0000269\|PubMed:12235007}. Note=Colocalizes with BMP1 in the Golgi. {ECO:0000250}.
Tissue Specificity	Widely expressed with highest levels in aorta, stomach, lower gastrointestinal tract, placenta, uterus, thyroid tissue and breast. Up-regulated in epithelial ovarian tumors. Not expressed in normal ovaries. Also highly expressed at the tumor periphery of lung carcinoma tissue but not within the tumor. Overexpressed in breast cancers. {ECO:0000269\|PubMed:11550156, ECO:0000269\|PubMed:12235007, ECO:0000269\|PubMed:15082792, ECO:0000269\|PubMed:23946676}.

Periostin (F-10) - sc-398631 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

Periostin (F-10): sc-398631. Western blot analysis of Periostin expression in human stomach tissue extract.

Periostin (C-20) - sc-49479 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Periostin (C-20): sc-49479. Immunoperoxidase staining of formalin fixed, paraffin-embedded human nasopharynx tissue showing cytoplasmic and nuclear staining of respiratory epithelial cells.

Periostin (S-15) - sc-49480 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Periostin (S-15): sc-49480. Immunoperoxidase staining of formalin fixed, paraffin-embedded human bronchus tissue showing cytoplasmic staining of respiratory epithelial cells.

Periostin (H-300) - sc-67233 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

Periostin (H-300): sc-67233. Immunoperoxidase staining of formalin fixed, paraffin-embedded human bronchus tissue showing cytoplasmic staining of respiratory epithelial cells.

Anti-Periostin antibody - ab14041 from Abcam

Prices	$403.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

ab14041 staining Periostin in human differentiated cardiac stem cells by Flow Cytometry. Cells were fixed with paraformaldehyde and permeabilized with permeabilization buffer. The sample was incubated with the primary antibody (1/800 in permeabilization buffer) for 1 hour at 4°C. ab175651, an Alexa Fluor® 405-conjugated donkey polyclonal anti-rabbit IgG (1/1000) was used as the secondary antibody.Gating Strategy: Isotype negative control (white). See Abreview

Anti-Periostin antibody - ab92460 from Abcam

Prices	$385.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-Periostin antibody (ab92460) at 1/1000 dilution + rat lung lysate

Anti-Periostin antibody - ab79946 from Abcam

Prices	$384.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-Periostin antibody (ab79946) at 1 µg/ml (blocked with 3% milk) + Breast (Human) Cytoplasmic Lysate - tumor tissue (ab30085) at 10 µgSecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/10000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Periostin antibody - ab152099 from Abcam

Prices	$384.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-Periostin antibody (ab152099) at 1/1000 dilution + H1299 whole cell lysate at 30 µg

Anti-Periostin antibody - ab83739 from Abcam

Prices	$376.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-Periostin antibody (ab83739) at 1 µg/ml + 293T cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-Periostin antibody - ab178537 from Abcam

Prices	$376.00
Sizes	200 µl
Host	Goat
Clonality	Polyclonal

Anti-Periostin antibody (ab178537) at 2 µg/ml + MCF7 cell line lysate at 35 µgdeveloped using the ECL technique

Anti-Periostin antibody [47] - ab85112 from Abcam

Prices	$376.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	47

Anti-Periostin antibody [47] (ab85112) at 1/500 dilution + HeLa cell lysate transfected with human periostin gene expression vector

Anti-Periostin antibody [EPR6989(N)(B)] - ab172615 from Abcam

Prices	$379.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR6989(N)(B)

All lanes : Anti-Periostin antibody [EPR6989(N)(B)] (ab172615) at 1/1000 dilutionLane 1 : MCF7 cell lysateLane 2 : 293T cell lysateLane 3 : HeLa cell lysateLane 4 : BxPC-3 cell lysateLysates/proteins at 10 µg per lane.

Anti-POSTN / Periostin Antibody - LS-C17033 from LifeSpan Bioscience

Prices	$710.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-POSTN / Periostin Antibody (aa24-811) - LS-C37925 from LifeSpan Bioscience

Prices	$465.00
Sizes	100 µg
Host	Rat
Clonality	Monoclonal

Anti-POSTN / Periostin Antibody (aa24-811) - LS-C73940 from LifeSpan Bioscience

Prices	$575.00
Sizes	500 µg
Host	Rat
Clonality	Monoclonal

Anti-POSTN / Periostin Antibody (N-Terminus) - LS-C73939 from LifeSpan Bioscience

Prices	$485.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-POSTN / Periostin Antibody - LS-C91127 from LifeSpan Bioscience

Prices	$605.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

Anti-POSTN / Periostin Antibody - LS-C131146 from LifeSpan Bioscience

Prices	$445.00
Sizes	100 µg
Host	Sheep
Clonality	Polyclonal

Anti-POSTN / Periostin Antibody (aa24-811, clone 345613) - LS-C150232 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rat
Clonality	Monoclonal
Clone	345613

Anti-POSTN / Periostin Antibody (aa694-724, APC) - LS-C280440 from LifeSpan Bioscience

Prices	$530.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-POSTN / Periostin Antibody (aa694-724, AP) - LS-C280439 from LifeSpan Bioscience

Prices	$530.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-POSTN / Periostin Antibody (aa694-724, Biotin) - LS-C280441 from LifeSpan Bioscience

Prices	$530.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-POSTN / Periostin Antibody (aa694-724, FITC) - LS-C280442 from LifeSpan Bioscience

Prices	$530.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-POSTN / Periostin Antibody (aa694-724, PE) - LS-C280444 from LifeSpan Bioscience

Prices	$530.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-POSTN / Periostin Antibody (aa694-724, Azide-free, HRP) - LS-C280443 from LifeSpan Bioscience

Prices	$530.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

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