| Gene Symbol | Inmt |
|---|---|
| Entrez Gene | 21743 |
| Alt Symbol | Temt |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | indolethylamine N-methyltransferase |
| Other Description | amine N-methyltransferase|aromatic alkylamine N-methyltransferase|arylamine N-methyltransferase|indolamine N-methyltransferase|nicotine N-methyltransferase|thioether S-methyltransferase |
| Swissprots | Q9CZ50 P40936 |
| Accessions | EDK98722 EDK98723 EDK98724 P40936 AK002281 BAB21985 AK013010 BAB28594 BC013518 AAH13518 M88694 AAA62365 NM_009349 NP_033375 |
| Function | Catalyzes the N-methylation of tryptamine and structurally related compounds (By similarity). Functions as thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2-methylthioethylamine, 2-methylthioethanol, methyl-n- propyl sulfide and diethyl sulfide. Plays an important role in the detoxification of selenium compounds. {ECO:0000250, ECO:0000269|PubMed:3350800}. |
| Subcellular Location | Cytoplasm {ECO:0000269|PubMed:3350800}. |
| Tissue Specificity | Detected in lung and liver (at protein level). {ECO:0000269|PubMed:3350800}. |
| Top Pathways | Selenocompound metabolism, Tryptophan metabolism |