Gene Symbol | RAB11FIP2 |
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Entrez Gene | 22841 |
Alt Symbol | Rab11-FIP2, nRip11 |
Species | Human |
Gene Type | protein-coding |
Description | RAB11 family interacting protein 2 (class I) |
Other Description | RAB11-FIP2 long isoform|rab11 family-interacting protein 2 |
Swissprots | A6NEI4 Q3I768 Q9Y2F0 Q7L804 |
Accessions | EAW49423 Q7L804 AB023158 BAA76785 AY037299 AAK68635 BC075073 AAH75073 BC075074 AAH75074 BM975322 BX647717 DQ013303 AAY67796 XM_005269629 XP_005269686 XM_011539511 XP_011537813 XM_011539512 XP_011537814 XM_011539513 XP_011537815 NM_014904 NP_055719 |
Function | A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity. {ECO:0000269|PubMed:12364336, ECO:0000269|PubMed:15304524, ECO:0000269|PubMed:16251358, ECO:0000269|PubMed:16775013, ECO:0000269|PubMed:19542231}. |
Subcellular Location | Cell membrane; Peripheral membrane protein. Recycling endosome membrane; Peripheral membrane protein. Note=Translocates with RAB11A from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane. |
Top Pathways | Endocytosis |
Human RAB11-FIP2 full length protein - ab153189 from Abcam
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Human RAB11-FIP2 peptide - ab95920 from Abcam
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RAB11FIP2 / Rab11-FIP2 Antibody Blocking Peptide - LS-E7851 from LifeSpan Bioscience
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RAB11FIP2 / Rab11-FIP2 Antibody Blocking Peptide - LS-E19893 from LifeSpan Bioscience
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Recombinant Human RAB11FIP2 Protein - H00022841-P01 from Novus Biologicals
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RAB11FIP2-Antibody-Center-Blocking-peptide - BP5475c from Abgent, a WuXi AppTec company
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RAB11FIP2 Blocking Peptide - 33R-5150 from Fitzgerald
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RAB11FIP2 Blocking Peptide - abx063745 from Abbexa
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RAB11FIP2 - H00022841-P01 from Acris Antibodies
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RAB11FIP2 fusion protein - ag12332 from Proteintech Group
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RAB11FIP2 fusion protein - Ag12736 from Proteintech Group
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RAB11FIP2 Blocking Peptide - CBP2551 from Cohesion Biosciences
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Recombinant Human Rab11 family-interacting protein 2(RAB11FIP2) - CSB-YP755487HU CSB-EP755487HU CSB-BP755487HU CSB-MP755487HU from Cusabio
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RAB11FIP2 (full length, N-term HIS tag) - TP760243 from Acris Antibodies
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RAB11FIP2 Recombinant Protein Antigen - NBP1-82949PEP from Novus Biologicals
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RAB11FIP2 Peptide, Human - M34GP12817H from Creative Peptides
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Rab11 family-interacting protein 2 (RAB11FIP2), Recombinant Protein - MBS1432413 from MyBioSource
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RAB11FIP2 peptide - orb218414 from Biorbyt
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Recombinant Human RAB11FIP2 Protein, His-tagged - RAB11FIP2-394H from Creative Biomart
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