THBS4

Gene Symbol THBS4
Entrez Gene 7060
Alt Symbol TSP-4, TSP4
Species Human
Gene Type protein-coding
Description thrombospondin 4
Other Description thrombospondin-4
Swissprots P35443 Q86TG2 B2R909
Accessions AAS66982 EAW95841 P35443 AK302842 BAH13818 AK313587 BAG36356 BC050456 AAH50456 DC310687 DC342285 DC376500 Z19585 CAA79635 XM_011543614 XP_011541916 NM_001306212 NP_001293141 NM_001306213 NP_001293142 NM_001306214 NP_001293143 NM_003248 NP_003239
Function Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions and is involved in various processes including cellular proliferation, migration, adhesion and attachment, inflammatory response to CNS injury, regulation of vascular inflammation and adaptive responses of the heart to pressure overload and in myocardial function and remodeling. Binds to structural extracellular matrix (ECM) proteins and modulates the ECM in response to tissue damage, contributing to cardioprotective and adaptive ECM remodeling. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors and protects myocardium from pressure overload. May contribute to spinal presynaptic hypersensitivity and neuropathic pain states after peripheral nerve injury. May play a role in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury in a NOTCH1-dependent manner (By simi
Subcellular Location Endoplasmic reticulum {ECO:0000250}. Sarcoplasmic reticulum {ECO:0000250}. Secreted. Secreted, extracellular space {ECO:0000250}. Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Top Pathways Focal adhesion, ECM-receptor interaction, Phagosome, Malaria, PI3K-Akt signaling pathway

Thrombospondin 4 (C-20)-R - sc-7657-R from Santa Cruz Biotechnology

Prices $61.00
Sizes 100 µg/0.5 ml
Host Rabbit
Clonality Polyclonal
Thrombospondin 4 (C-20)-R: sc-7657-R. Western blot analysis of Thrombospondin 4 expression in A-431 whole cell lysate.

Thrombospondin 4 (F-7) - sc-390734 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Thrombospondin 4 (F-7): sc-390734. Western blot analysis of Thrombospondin 4 expression in mouse testis (A) and rat testis (B) tissue extracts.

Thrombospondin 4 (G-10) - sc-28293 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Thrombospondin 4 (G-10): sc-28293. Immunoperoxidase staining of formalin fixed, paraffin-embedded human testis tissue showing cytoplasmic staining of Leydig cells (low and high magnification). Kindly provided by The Swedish Human Protein Atlas (HPA) program.

Thrombospondin 4 (G-6) - sc-55464 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Thrombospondin 4 (G-6): sc-55464. Western blot analysis of human recombinant Thrombospondin 4 fusion protein.

Thrombospondin 4 (H-100) - sc-20646 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-THBS4 antibody - ab121094 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-THBS4 antibody (ab121094) at 1 µg/ml + Skeletal Muscle (Human) Tissue Lysate - adult normal tissue (ab29330) at 10 µgSecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-THBS4 antibody - ab76861 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-THBS4 antibody (ab76861) at 1/500 dilutionLane 1 : THBS4 transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-THBS4 antibody - C-terminal - ab156258 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-THBS4 antibody - C-terminal (ab156258) at 1/100 dilution + NCI-H460 cell line lysate at 35 µg

Anti-THBS4 antibody - N-terminal - ab176116 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of Human lung cells labeling THBS4  with ab176116 at 20 μg/ml.

Anti-THBS4 / Thrombospondin 4 Antibody (aa932-961, Biotin) - LS-C271437 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-THBS4 / Thrombospondin 4 Antibody (aa932-961, AP) - LS-C271435 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-THBS4 / Thrombospondin 4 Antibody (aa932-961, APC) - LS-C271436 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-THBS4 / Thrombospondin 4 Antibody (aa932-961, FITC) - LS-C271438 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-THBS4 / Thrombospondin 4 Antibody (aa932-961, Azide-free, HRP) - LS-C271439 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-THBS4 / Thrombospondin 4 Antibody (aa932-961, PE) - LS-C271440 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-THBS4 / Thrombospondin 4 Antibody (aa708-963, Biotin) - LS-C299945 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-THBS4 / Thrombospondin 4 Antibody (aa561-610) - LS-C199651 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human breast carcinoma, using THBS4 Antibody. The sample on the right was incubated with synthetic peptide.

Anti-THBS4 / Thrombospondin 4 Antibody (aa644-925, Biotin) - LS-C300189 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-THBS4 / Thrombospondin 4 Antibody (aa662-923, Biotin) - LS-C300191 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-THBS4 / Thrombospondin 4 Antibody (aa644-925, FITC) - LS-C302474 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-THBS4 / Thrombospondin 4 Antibody (aa932-961) - LS-C156215 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
THBS4 Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The THBS4 antibody detected the THBS4 protein (arrow).

Anti-THBS4 / Thrombospondin 4 Antibody (aa662-923, FITC) - LS-C302475 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-THBS4 / Thrombospondin 4 Antibody (aa708-963, FITC) - LS-C302516 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-THBS4 / Thrombospondin 4 Antibody (aa932-961) - LS-C325714 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-THBS4 / Thrombospondin 4 Antibody (aa644-925) - LS-C296621 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant Thrombospondin 4 / THBS4.
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