THBS4

Gene Symbol	THBS4
Entrez Gene	7060
Alt Symbol	TSP-4, TSP4
Species	Human
Gene Type	protein-coding
Description	thrombospondin 4
Other Description	thrombospondin-4
Swissprots	P35443 Q86TG2 B2R909
Accessions	AAS66982 EAW95841 P35443 AK302842 BAH13818 AK313587 BAG36356 BC050456 AAH50456 DC310687 DC342285 DC376500 Z19585 CAA79635 XM_011543614 XP_011541916 NM_001306212 NP_001293141 NM_001306213 NP_001293142 NM_001306214 NP_001293143 NM_003248 NP_003239
Function	Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions and is involved in various processes including cellular proliferation, migration, adhesion and attachment, inflammatory response to CNS injury, regulation of vascular inflammation and adaptive responses of the heart to pressure overload and in myocardial function and remodeling. Binds to structural extracellular matrix (ECM) proteins and modulates the ECM in response to tissue damage, contributing to cardioprotective and adaptive ECM remodeling. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors and protects myocardium from pressure overload. May contribute to spinal presynaptic hypersensitivity and neuropathic pain states after peripheral nerve injury. May play a role in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury in a NOTCH1-dependent manner (By simi
Subcellular Location	Endoplasmic reticulum {ECO:0000250}. Sarcoplasmic reticulum {ECO:0000250}. Secreted. Secreted, extracellular space {ECO:0000250}. Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Top Pathways	Focal adhesion, ECM-receptor interaction, Phagosome, Malaria, PI3K-Akt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human THBS4 full length protein - ab159695 from Abcam Category Protein Source Wheat germ Species Human

Human THBS4 full length protein - ab182812 from Abcam Category Protein Source E. coli Species Human

Human THBS4 protein fragment - ab159696 from Abcam Category Protein Source Wheat germ Species Human

THBS4 / Thrombospondin 4 Antibody Blocking Peptide - LS-E31273 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human Thrombospondin-4 Protein - H00007060-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Thrombospondin-4 Protein - H00007060-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Thrombospondin-4, CF - 2390-TH-050 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived, Ala22-Asn961, with a C-terminal 10-His tag

Human Thrombospondin 4 Protein - abx069284 from Abbexa Category Protein Source E.coli Species Human

Thrombospondin-4 (THBS4) - H00007060-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Thrombospondin-4 (THBS4) - H00007060-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Thrombospondin-4 (THBS4) - H00007060-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Thrombospondin-4 (THBS4) - H00007060-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Thrombospondin-4 (THBS4) (N-term) Control Peptide - AP55423CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

Thrombospondin 4 (THBS4), Human - 20-8850 from ARP American Research Products Category Protein Prices $417.00 Sizes 50 µg Source E.coli Species Human

THBS4 Peptide - 6843P from ProSci Category Peptide Species Human

Recombinant Human Thrombospondin 4, His-tagged - THBS4-507H from Creative Biomart Category Protein Source Chinese HamsterOvary cell line, CHO-derived.

Recombinant Human THBS4, GST-tagged - THBS4-121H from Creative Biomart Category Protein Source Wheat germ Species Human

Recombinant Thrombospondin 4 (THBS4) - RPD824Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Thrombospondin 4 (THBS4) - RPD824Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Thrombospondin 4 (THBS4) - RPD824Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Thrombospondin 4 (THBS4) - RPD824Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Recombinant Thrombospondin 4 (THBS4) - RPD824Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Thrombospondin-4(THBS4) ,partial - CSB-YP023490HU CSB-EP023490HU CSB-BP023490HU CSB-MP023490HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human Thrombospondin-4 Protein, CF - 2390-TH from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Chinese Hamster Ovary cell line, CHO-derived Ala22-Asn961, with a C-terminal 10-His tag Species Human

Thrombospondin 4 (THBS4) - RPU143995 from Biomatik Category Protein Prices $191.40, $382.80, $574.20 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Human

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