Gene Symbol | LANCL2 |
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Entrez Gene | 55915 |
Alt Symbol | GPR69B, TASP |
Species | Human |
Gene Type | protein-coding |
Description | LanC lantibiotic synthetase component C-like 2 (bacterial) |
Other Description | G protein-coupled receptor 69B|LanC (bacterial lantibiotic synthetase component C)-like 2|lanC-like protein 2|testis-specific adriamycin sensitivity protein |
Swissprots | Q6NSL4 Q8TCQ3 B2R8D4 Q9NS86 Q9BSR1 |
Accessions | AAQ93360 EAL23810 EAW50968 Q9NS86 AA994905 AB035966 BAA96800 AF353942 AAK83286 AJ278245 CAC21715 AK095857 BAG53147 AK225958 AK301747 BAG63209 AK307204 AK313326 BAG36131 AL713665 CAD28471 BC004887 AAH04887 BC070049 AAH70049 BF590020 BI869599 XM_011515448 XP_011513750 NM_018697 NP_061167 |
Function | Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes. {ECO:0000269|PubMed:19667068}. |
Subcellular Location | Nucleus. Cytoplasm. Cell membrane. Note=Localizes to the juxta-nuclear vesicles. Associates with the cortical actin cytoskeleton. Cholesterol depletion by methyl-beta- cyclodextrin causes partial dissociation from the cell membrane in vitro and an enhanced cell detachment from the matrix in vivo. Membrane-association is important for the increased cellular sensitivity to an anticancer drug (adriamycin). |
Tissue Specificity | Expressed in brain and testis. {ECO:0000269|PubMed:11762191}. |
LANCL2 (D-19) - sc-79563 from Santa Cruz Biotechnology
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LANCL2 (P-15) - sc-79565 from Santa Cruz Biotechnology
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LANCL2 (Y-17) - sc-79566 from Santa Cruz Biotechnology
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Anti-LANCL2 antibody - ab88860 from Abcam
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Anti-LANCL2 antibody - ab67676 from Abcam
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Anti-LANCL2 antibody [1C5] - ab131645 from Abcam
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Anti-LANCL2 antibody [2A11] - ab128481 from Abcam
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Anti-TASP / LANCL2 Antibody (aa212-450, clone 1C5) - LS-C336946 from LifeSpan Bioscience
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Anti-TASP / LANCL2 Antibody (clone 2A11) - LS-C175170 from LifeSpan Bioscience
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Anti-TASP / LANCL2 Antibody - LS-C308710 from LifeSpan Bioscience
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Anti-TASP / LANCL2 Antibody (aa179-228) - LS-C112018 from LifeSpan Bioscience
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Anti-TASP / LANCL2 Antibody (aa287-336) - LS-C112019 from LifeSpan Bioscience
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LANCL2 Antibody (2A11) - NBP2-03893 from Novus Biologicals
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LANCL2 Antibody - NBP1-83340 from Novus Biologicals
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LANCL2 Antibody - NBP1-83339 from Novus Biologicals
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LANCL2 Antibody - H00055915-B01 from Novus Biologicals
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LANCL2 Antibody - H00055915-B01P from Novus Biologicals
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LANCL2 Polyclonal Antibody - bs-5765R from Bioss
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Anti-LANCL2 antibody produced in rabbit - HPA029535 from Sigma-Aldrich
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Anti-LANCL2 antibody produced in mouse - SAB1400637 from Sigma-Aldrich
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Anti-LANCL2 antibody produced in rabbit - SAB2106086 from Sigma-Aldrich
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Anti-LANCL2 antibody produced in rabbit - HPA019711 from Sigma-Aldrich
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LANCL2 antibody - middle region (ARP57285_P050) - ARP57285_P050 from Aviva Systems Biology
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LANCL2 antibody - middle region (ARP57286_P050) - ARP57286_P050 from Aviva Systems Biology
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LANCL2 antibody [N1C1] - GTX119561 from GeneTex
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