Gene Symbol | MAP3K3 |
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Entrez Gene | 4215 |
Alt Symbol | MAPKKK3, MEKK3 |
Species | Human |
Gene Type | protein-coding |
Description | mitogen-activated protein kinase kinase kinase 3 |
Other Description | MAP/ERK kinase kinase 3|MAPK/ERK kinase kinase 3|MEK kinase 3|MEKK 3 |
Swissprots | Q8N3I9 B2RCW2 Q5BKZ6 Q99759 D3DU15 |
Accessions | CAF32906 EAW94297 EAW94298 EAW94299 Q99759 AF172823 AAQ13617 AK022333 AK225784 AK308152 AK315305 BAG37709 AL834303 CAD38973 AM392833 CAL37711 AX775739 CAE11569 AX775741 CAE11570 BC008336 AAH08336 BC010464 BC018021 BC090859 AAH90859 BC093672 AAH93672 BC093674 AAH93674 BC143224 BC143235 BM479726 BM728104 BM800091 BQ643432 BU633068 DQ454151 ABE11554 U78876 AAB41729 XM_005257376 XP_005257433 XM_005257377 XP_005257434 XM_005257378 XP_005257435 XR_934463 NM_002401 NP_002392 NM_203351 NP_976226 |
Function | Component of a protein kinase signal transduction cascade. Mediates activation of the NF-kappa-B, AP1 and DDIT3 transcriptional regulators. {ECO:0000269|PubMed:12912994, ECO:0000269|PubMed:14661019, ECO:0000269|PubMed:14743216, ECO:0000269|PubMed:9006902}. |
Top Pathways | GnRH signaling pathway, MAPK signaling pathway, Neurotrophin signaling pathway, HTLV-I infection |
Active human MEKK3 full length protein - ab85297 from Abcam
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Human MEKK3 full length protein - ab152523 from Abcam
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Human MEKK3 protein fragment - ab152524 from Abcam
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MAP3K3 / MEKK3 Antibody Blocking Peptide - LS-E3112 from LifeSpan Bioscience
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Recombinant Human MEKK3 Protein - H00004215-Q01 from Novus Biologicals
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Recombinant Human MEKK3 Protein - H00004215-P01 from Novus Biologicals
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MEKK3 Peptide - P2888 from Novus Biologicals
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MEKK3-Antibody-Center-Blocking-Peptide - BP7909c from Abgent, a WuXi AppTec company
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MEKK3 Blocking Peptide - abx062161 from Abbexa
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MAP3K3 - H00004215-P01-10 from Acris Antibodies
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MAP3K3 - H00004215-P01-25 from Acris Antibodies
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MAP3K3 - H00004215-Q01-10 from Acris Antibodies
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MAP3K3 - H00004215-Q01-25 from Acris Antibodies
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MAP3K3 - P5590 from Acris Antibodies
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MAP3K3 fusion protein - Ag15223 from Proteintech Group
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Recombinant Human MAP3K3, GST-tagged, Active - MAP3K3-352H from Creative Biomart
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Recombinant Human MAP3K3 - MAP3K3-30192TH from Creative Biomart
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Recombinant Human Mitogen-Activated Protein Kinase Kinase Kinase 3, GST-tagged - MAP3K3-1259H from Creative Biomart
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MEKK3 Blocking Peptide - CBP3267 from Cohesion Biosciences
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MEK Kinase-3 (N96) Peptide - BS2129P from Bioworld Technology
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Recombinant Human Mitogen-activated protein kinase kinase kinase 3(MAP3K3) - CSB-YP013425HU CSB-EP013425HU CSB-BP013425HU CSB-MP013425HU from Cusabio
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MAP3K3 (full length, N-term HIS tag, transcript variant 2) - TP760320 from Acris Antibodies
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Recombinant Human MEKK3 His - CSI13421 from Cell Science
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MEKK3 Recombinant Protein Antigen - NBP2-34004PEP from Novus Biologicals
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MEKK3-Antibody-N-term-Blocking-Peptide - BP7909a from Abgent, a WuXi AppTec company
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