MAP3K3

Gene Symbol MAP3K3
Entrez Gene 4215
Alt Symbol MAPKKK3, MEKK3
Species Human
Gene Type protein-coding
Description mitogen-activated protein kinase kinase kinase 3
Other Description MAP/ERK kinase kinase 3|MAPK/ERK kinase kinase 3|MEK kinase 3|MEKK 3
Swissprots Q8N3I9 B2RCW2 Q5BKZ6 Q99759 D3DU15
Accessions CAF32906 EAW94297 EAW94298 EAW94299 Q99759 AF172823 AAQ13617 AK022333 AK225784 AK308152 AK315305 BAG37709 AL834303 CAD38973 AM392833 CAL37711 AX775739 CAE11569 AX775741 CAE11570 BC008336 AAH08336 BC010464 BC018021 BC090859 AAH90859 BC093672 AAH93672 BC093674 AAH93674 BC143224 BC143235 BM479726 BM728104 BM800091 BQ643432 BU633068 DQ454151 ABE11554 U78876 AAB41729 XM_005257376 XP_005257433 XM_005257377 XP_005257434 XM_005257378 XP_005257435 XR_934463 NM_002401 NP_002392 NM_203351 NP_976226
Function Component of a protein kinase signal transduction cascade. Mediates activation of the NF-kappa-B, AP1 and DDIT3 transcriptional regulators. {ECO:0000269|PubMed:12912994, ECO:0000269|PubMed:14661019, ECO:0000269|PubMed:14743216, ECO:0000269|PubMed:9006902}.
Top Pathways GnRH signaling pathway, MAPK signaling pathway, Neurotrophin signaling pathway, HTLV-I infection

MEKK3 (D36G5) Rabbit mAb - 5727 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D36G5
Western blot analysis of extracts from various cell types using MEKK3 (D36G5) Rabbit mAb.

MEK kinase-2 (H-9) - sc-398091 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MEK kinase-2 (H-9): sc-398091. Western blot analysis of MEK kinase-2 expression in Jurkat (A), K-562 (B), MCF7 (C), Ramos (D) and BJAB (E) whole cell lysates.

MEK kinase-3 (H-70) - sc-28769 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
MEK kinase-3 (H-70): sc-28769. Immunofluorescence staining of normal mouse intestine frozen section showing cytoplasmic staining.

MEK kinase-3 (D-17) - sc-6844 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MEK kinase-3 (C-20) - sc-6843 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MEK kinase-3 (40) - sc-136260 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
MEK kinase-3 (40): sc-136260. Western blot analysis of MEK kinase-3 expression in HeLa whole cell lysate.

p-MEK kinase-3 (Ser 337) - sc-28044 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
p-MEK kinase-3 (Ser 337)-R: sc-28044-R. Western blot analysis of MEK kinase-3 phosphorylation in non-transfected: sc-117752 (A) and mouse MEK kinase-3 transfected: sc-125599 (B) 293T whole cell lysates.

Anti-MEKK3 antibody - ab154362 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MEKK3 antibody (ab154362) at 1/1000 dilutionLane 1 : 293T whole cell lysateLane 2 : A431 whole cell lysateLane 3 : H1299 whole cell lysateLane 4 : HeLa S2 whole cell lysateLane 5 : HepG2 whole cell lysateLane 6 : MOLT4 whole cell lysateLane 7 : Raji whole cell lysateLysates/proteins at 30 µg per lane.

Anti-MEKK3 antibody - ab113296 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MEKK3 antibody (ab113296) at 0.4 µg/mlLane 1 : 293T whole cell lysate at 50 µgLane 2 : 293T whole cell lysate at 15 µgLane 3 : 293T whole cell lysate at 5 µgLane 4 : Jurkat whole cell lysate at 50 µgLane 5 : NIH3T3 whole cell lysate at 50 µgdeveloped using the ECL technique

Anti-MEKK3 antibody - ab65105 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MEKK3 antibody (ab65105) at 1/500 dilutionLane 1 : Extracts from HepG2 cellsLane 2 : Extracts from HepG2 cells with immunising peptide

Anti-MEKK3 antibody [ep599y] - ab40750 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone ep599y
Overlay histogram showing HeLa cells stained with ab40750 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab40750, 1/1000 dilution) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-rabbit IgG (H&L) (ab150077) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) (0.1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.

Anti-MEKK3 antibody [ep600y] - ab40756 from Abcam

Prices $391.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone ep600y
Anti-MEKK3 antibody [ep600y] (ab40756) at 1/1000 dilution + HeLa cell lysate at 10 µg

Anti-MAP3K3 / MEKK3 Antibody (clone 1H3) - LS-C197671 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1H3

Anti-MAP3K3 / MEKK3 Antibody (aa227-257, Biotin) - LS-C262569 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAP3K3 / MEKK3 Antibody (aa227-257, APC) - LS-C262570 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAP3K3 / MEKK3 Antibody (aa227-257, AP) - LS-C262571 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAP3K3 / MEKK3 Antibody (aa227-257, FITC) - LS-C262572 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAP3K3 / MEKK3 Antibody (aa227-257, Azide-free, HRP) - LS-C262573 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAP3K3 / MEKK3 Antibody (aa227-257, PE) - LS-C262574 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAP3K3 / MEKK3 Antibody IHC-plus™ - LS-B3753 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-MAP3K3 / MEKK3 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3753 dilution 1:100.

Anti-MAP3K3 / MEKK3 Antibody (Asn96) - LS-C176830 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of MEK Kinase-3 (N96) pAb in extracts from HepG2 cells.

Anti-MAP3K3 / MEKK3 Antibody (aa101-150) - LS-C119225 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from HepG2 cells, using MAP3K3 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-MAP3K3 / MEKK3 Antibody - LS-C311381 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MAP3K3 / MEKK3 Antibody - LS-C309207 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-MAP3K3 / MEKK3 Antibody (aa227-257) - LS-C329805 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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