MAP3K3

Gene Symbol	MAP3K3
Entrez Gene	4215
Alt Symbol	MAPKKK3, MEKK3
Species	Human
Gene Type	protein-coding
Description	mitogen-activated protein kinase kinase kinase 3
Other Description	MAP/ERK kinase kinase 3|MAPK/ERK kinase kinase 3|MEK kinase 3|MEKK 3
Swissprots	Q8N3I9 B2RCW2 Q5BKZ6 Q99759 D3DU15
Accessions	CAF32906 EAW94297 EAW94298 EAW94299 Q99759 AF172823 AAQ13617 AK022333 AK225784 AK308152 AK315305 BAG37709 AL834303 CAD38973 AM392833 CAL37711 AX775739 CAE11569 AX775741 CAE11570 BC008336 AAH08336 BC010464 BC018021 BC090859 AAH90859 BC093672 AAH93672 BC093674 AAH93674 BC143224 BC143235 BM479726 BM728104 BM800091 BQ643432 BU633068 DQ454151 ABE11554 U78876 AAB41729 XM_005257376 XP_005257433 XM_005257377 XP_005257434 XM_005257378 XP_005257435 XR_934463 NM_002401 NP_002392 NM_203351 NP_976226
Function	Component of a protein kinase signal transduction cascade. Mediates activation of the NF-kappa-B, AP1 and DDIT3 transcriptional regulators. {ECO:0000269|PubMed:12912994, ECO:0000269|PubMed:14661019, ECO:0000269|PubMed:14743216, ECO:0000269|PubMed:9006902}.
Top Pathways	GnRH signaling pathway, MAPK signaling pathway, Neurotrophin signaling pathway, HTLV-I infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MEK kinase-3 CRISPR/Cas9 KO Plasmid (h) - sc-404290 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK kinase-3 HDR Plasmid (h) - sc-404290-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK kinase-3 Double Nickase Plasmid (h) - sc-404290-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK kinase-3 Double Nickase Plasmid (h2) - sc-404290-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK kinase-3 CRISPR Activation Plasmid (h) - sc-404290-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK kinase-3 CRISPR Activation Plasmid (h2) - sc-404290-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK kinase-3 Lentiviral Activation Particles (h) - sc-404290-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK kinase-3 Lentiviral Activation Particles (h2) - sc-404290-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MEK kinase-3 siRNA (h) - sc-39108 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MEK kinase-3 shRNA Plasmid (h) - sc-39108-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MEK kinase-3 shRNA (h) Lentiviral Particles - sc-39108-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MEKK3 RNAi - H00004215-R06 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MEKK3 RNAi - H00004215-R05 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU101361 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK1145 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1144 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1146 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN12992 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12992 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MAP3K3 siRNA (Human) - CRH2866 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human MAP3K3 (NM_002401.3) - SHH337699 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human MAP3K3(NM_002401.3) - SHH174107 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human MAP3K3(NM_203351.1) - SHH174125 from Creative biogene Category siRNA Species Reactivities Human

Human MAP3K3 siRNA - orb263368 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

MAP3K3 shRNA Plasmid (Human) - CHH2866 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

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