Ifnlr1

Gene Symbol Ifnlr1
Entrez Gene 242700
Alt Symbol CRF2-12, Il28ra
Species Mouse
Gene Type protein-coding
Description interferon lambda receptor 1
Other Description IFN-lambda R1|IL-28 receptor subunit alpha|IL-28R-alpha|IL-28RA|class II cytokine receptor 12|cytokine receptor class-II member 12|cytokine receptor family 2 member 12|interferon-lambda receptor 1|interleukin 28 receptor alpha|interleukin-28 receptor subunit alpha
Swissprots Q6PEV1 Q8CGK5
Accessions EDL29971 Q8CGK5 AK141338 BAE24654 AK148133 AK205737 AY184376 AAN86129 BC057856 AAH57856 NM_174851 NP_777276
Function The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. Determines the cell type specificity of the lambda interferon action. Shows a more restricted pattern of expression in the epithelial tissues thereby limiting responses to lambda interferons primarily to epithelial cells of the respiratory, gastrointestinal, and reproductive tracts. Seems not to be essential for early virus- activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. {ECO:0000269|PubMed:18250457, ECO:0000269|PubMed:21518880}.
Subcellular Location Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Top Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

Interleukin-28 receptor subunit alpha (IL28RA), Mouse, ELISA Kit - CSB-EL011647MO from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

interleukin 28 receptor, alpha (interferon, lambda receptor) , ELISA Kit - MBS923645 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mouse Interleukin-28 receptor subunit alpha(IL28RA) ELISA kit - CSB-EL011647MO from Cusabio

Category ELISA Kit
Sensitivity Request Information
Range Request Information

Mouse Interleukin-28 receptor subunit alpha (IL28RA) ELISA Kit - EKC37210 from Biomatik

Category ELISA Kit
Prices $705.00, $2,820.00, $5,288.00
Sizes 96 t, 5x96t, 10x96t
Sensitivity 0.04 ng/ml
Range 10 ng/ml-0.16 ng/ml

Mouse IL28RA ELISA Kit - E057322 from Biobool

Category ELISA Kit

Mouse Ifnlr1 ELISA Kit - E086764 from Biobool

Category ELISA Kit

Mouse IL28RA ELISA Kit - orb408265 from Biorbyt

Category ELISA Kit
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