Gene Symbol | KIAA1033 |
---|---|
Entrez Gene | 23325 |
Alt Symbol | MRT43, SWIP |
Species | Human |
Gene Type | protein-coding |
Description | KIAA1033 |
Other Description | WASH complex subunit 7|strumpellin and WASH-interacting protein |
Swissprots | Q2M389 Q2NL83 Q8N5W7 Q9UPW7 Q9NVD6 Q8IW61 |
Accessions | EAW97758 EAW97759 EAW97760 EAW97761 Q2M389 AB028956 BAA82985 AF075010 AI753633 AK001657 BAA91816 AK001728 AK023146 AK026950 AK027218 AL137753 BC012556 BC031358 AAH31358 BC040936 AAH40936 BC104992 AAI04993 BC104994 AAI04995 BC110850 AAI10851 BC143373 AAI43374 XM_005268746 XP_005268803 XM_011538073 XP_011536375 XM_011538074 XP_011536376 XM_011538075 XP_011536377 XM_011538076 XP_011536378 XM_011538077 XP_011536379 XR_944511 NM_001293640 NP_001280569 NM_015275 NP_056090 |
Function | Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes sems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization, and which is involved in the regulation of the fission of tubules that serve as transport intermediates during endosome sorting (PubMed:19922875, PubMed:20498093). {ECO:0000250|UniProtKB:Q3UMB9, ECO:0000303|PubMed:21498477, ECO:0000305|PubMed:19922875, ECO:0000305|PubMed:20498093}. |
Subcellular Location | Early endosome {ECO:0000269|PubMed:23676666}. |
KIAA1033 CRISPR/Cas9 KO Plasmid (h) - sc-411716 from Santa Cruz Biotechnology
|
||||||||
KIAA1033 HDR Plasmid (h) - sc-411716-HDR from Santa Cruz Biotechnology
|
||||||||
KIAA1033 Double Nickase Plasmid (h) - sc-411716-NIC from Santa Cruz Biotechnology
|
||||||||
KIAA1033 Double Nickase Plasmid (h2) - sc-411716-NIC-2 from Santa Cruz Biotechnology
|
||||||||
KIAA1033 CRISPR Activation Plasmid (h) - sc-411716-ACT from Santa Cruz Biotechnology
|
||||||||
KIAA1033 CRISPR Activation Plasmid (h2) - sc-411716-ACT-2 from Santa Cruz Biotechnology
|
||||||||
KIAA1033 Lentiviral Activation Particles (h) - sc-411716-LAC from Santa Cruz Biotechnology
|
||||||||
KIAA1033 Lentiviral Activation Particles (h2) - sc-411716-LAC-2 from Santa Cruz Biotechnology
|
||||||||
KIAA1033 siRNA (h) - sc-96101 from Santa Cruz Biotechnology
|
||||||||
KIAA1033 shRNA Plasmid (h) - sc-96101-SH from Santa Cruz Biotechnology
|
||||||||
KIAA1033 shRNA (h) Lentiviral Particles - sc-96101-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU076351 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN11103 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11103 from Sigma-Aldrich
|
||||||||
KIAA1033 siRNA (Human) - CRH8181 from Cohesion Biosciences
|
||||||||
shRNA set against Human KIAA1033 (NM_015275.1) - SHH324667 from Creative biogene
|
||||||||
Human KIAA1033 siRNA - orb268683 from Biorbyt
|
||||||||
KIAA1033 shRNA Plasmid (Human) - CHH8181 from Cohesion Biosciences
|
||||||||
KIAA1033 miRNA 3'UTR clone - MiUTR1H-05243 from Creative biogene
|