Gene Symbol | NANS |
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Entrez Gene | 54187 |
Alt Symbol | HEL-S-100, SAS |
Species | Human |
Gene Type | protein-coding |
Description | N-acetylneuraminic acid synthase |
Other Description | N-acetylneuraminate synthase|N-acetylneuraminate-9-phosphate synthase|N-acetylneuraminic acid phosphate synthase|epididymis secretory protein Li 100|sialic acid phosphate synthase|sialic acid synthase |
Swissprots | Q9NVD4 Q8WUV9 Q9NR45 Q9BWS6 B2RE98 |
Accessions | EAW58866 EAW58867 EAW58868 EAW58869 Q9NR45 AF161387 AAF28947 AF257466 AAF75261 AK001659 BAA91818 AK091184 AK316608 BAG38195 AL526281 BC000008 AAH00008 BC019315 AAH19315 BQ446501 DQ892167 ABM83093 DQ895361 ABM86287 FJ224349 ACI46041 XM_011518787 XP_011517089 XM_011518788 XP_011517090 NM_018946 NP_061819 |
Function | Produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3- deoxy-D-glycero-D-galacto-nononic acid (KDN). Can also use N- acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of Neu5Ac and KDN, respectively. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Amino sugar and nucleotide sugar metabolism |
NANS (B-1) - sc-514091 from Santa Cruz Biotechnology
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NANS (B-6) - sc-374133 from Santa Cruz Biotechnology
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NANS (N-14) - sc-163115 from Santa Cruz Biotechnology
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NANS (D-8) - sc-374132 from Santa Cruz Biotechnology
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NANS (H-300) - sc-135314 from Santa Cruz Biotechnology
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NANS (L-14) - sc-163114 from Santa Cruz Biotechnology
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Anti-NANS antibody - ab88899 from Abcam
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Anti-NANS antibody - ab57258 from Abcam
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Anti-NANS antibody [AT1G6] - ab122983 from Abcam
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Anti-NANS Antibody (C-Terminus) - LS-C151959 from LifeSpan Bioscience
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Anti-NANS Antibody (aa133-182) - LS-C151960 from LifeSpan Bioscience
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Anti-NANS Antibody (aa260-360, Azide-free) - LS-C328001 from LifeSpan Bioscience
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Anti-NANS Antibody (clone AT1G6) IHC-plus⢠- LS-B8963 from LifeSpan Bioscience
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Anti-NANS Antibody (aa54-359) - LS-C185694 from LifeSpan Bioscience
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NANS Antibody - NBP1-87088 from Novus Biologicals
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NANS Antibody - NBP2-19470 from Novus Biologicals
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NANS Antibody - NBP1-31440 from Novus Biologicals
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NANS Antibody (3G6) - H00054187-M01 from Novus Biologicals
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NANS Antibody (1G6) - NBP1-97938 from Novus Biologicals
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NANS Antibody - H00054187-A01 from Novus Biologicals
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NANS Antibody - H00054187-B01P from Novus Biologicals
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Monoclonal Anti-NANS antibody produced in mouse - WH0054187M1 from Sigma-Aldrich
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Anti-NANS antibody produced in mouse - SAB1409454 from Sigma-Aldrich
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Anti-NANS antibody produced in rabbit - HPA019223 from Sigma-Aldrich
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NANS Antibody (OALA07311) - OALA07311 from Aviva Systems Biology
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