| Gene Symbol |
NANS
|
| Entrez Gene |
54187
|
| Alt Symbol |
HEL-S-100, SAS
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
N-acetylneuraminic acid synthase
|
| Other Description |
N-acetylneuraminate synthase|N-acetylneuraminate-9-phosphate synthase|N-acetylneuraminic acid phosphate synthase|epididymis secretory protein Li 100|sialic acid phosphate synthase|sialic acid synthase
|
| Swissprots |
Q9NVD4 Q8WUV9 Q9NR45 Q9BWS6 B2RE98
|
| Accessions |
EAW58866 EAW58867 EAW58868 EAW58869 Q9NR45 AF161387 AAF28947 AF257466 AAF75261 AK001659 BAA91818 AK091184 AK316608 BAG38195 AL526281 BC000008 AAH00008 BC019315 AAH19315 BQ446501 DQ892167 ABM83093 DQ895361 ABM86287 FJ224349 ACI46041 XM_011518787 XP_011517089 XM_011518788 XP_011517090 NM_018946 NP_061819
|
| Function |
Produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3- deoxy-D-glycero-D-galacto-nononic acid (KDN). Can also use N- acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of Neu5Ac and KDN, respectively.
|
| Tissue Specificity |
Ubiquitous.
|
| Top Pathways |
Amino sugar and nucleotide sugar metabolism
|