EPS15L1

Gene Symbol EPS15L1
Entrez Gene 58513
Alt Symbol EPS15R
Species Human
Gene Type protein-coding
Description epidermal growth factor receptor pathway substrate 15-like 1
Other Description epidermal growth factor receptor substrate 15-like 1|epidermal growth factor receptor substrate EPS15R|eps15-related protein
Swissprots A5PL29 Q9UBC2 A2RRF3 B4DKA3
Accessions EAW84542 EAW84543 EAW84544 EAW84545 Q9UBC2 AB015346 BAA88118 AF110265 AAF21930 AK023744 AK024166 BAG51266 AK025770 AK291359 BAF84048 AK296473 BAG59115 AK297428 BAG59856 AK299001 BAG61087 AL110270 CAH10724 AU121887 BC037558 BC051873 BC067114 BC131590 AAI31591 BC142662 AAI42663 BC142716 AAI42717 BU075732 CA311813 CA446537 DC416977 NM_001258374 NP_001245303 NM_001258375 NP_001245304 NM_001258376 NP_001245305 NM_021235 NP_067058 NR_047665 NR_047666
Function Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. {ECO:0000269|PubMed:22648170, ECO:0000269|PubMed:9407958}.
Subcellular Location Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Nucleus {ECO:0000250}. Membrane, coated pit {ECO:0000250}. Note=Localized to plasma membrane coated pits. {ECO:0000250}.

EPS15L1 - MBS1267600 from MyBioSource

Species Human
Accession BC131590

Human EPS15L1 ORF Clone(NM_021235.2) - CDCL162513 from Creative Biomart

Species Human
Accession NM_021235.2

Human EPS15L1 ORF clone (NM_001258374.1) - CDCR060934 from Creative biogene

Species Human

Human EPS15L1 ORF clone (NM_001258375.1) - CDCR060936 from Creative biogene

Species Human

Human EPS15L1 ORF clone (NM_001258376.1) - CDCR060938 from Creative biogene

Species Human

Human EPS15L1 ORF Clone (BC131590) - CDCS415328 from Creative biogene

Species Human
Accession Q9UBC2
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