Gene Symbol | EPS15L1 |
---|---|
Entrez Gene | 58513 |
Alt Symbol | EPS15R |
Species | Human |
Gene Type | protein-coding |
Description | epidermal growth factor receptor pathway substrate 15-like 1 |
Other Description | epidermal growth factor receptor substrate 15-like 1|epidermal growth factor receptor substrate EPS15R|eps15-related protein |
Swissprots | A5PL29 Q9UBC2 A2RRF3 B4DKA3 |
Accessions | EAW84542 EAW84543 EAW84544 EAW84545 Q9UBC2 AB015346 BAA88118 AF110265 AAF21930 AK023744 AK024166 BAG51266 AK025770 AK291359 BAF84048 AK296473 BAG59115 AK297428 BAG59856 AK299001 BAG61087 AL110270 CAH10724 AU121887 BC037558 BC051873 BC067114 BC131590 AAI31591 BC142662 AAI42663 BC142716 AAI42717 BU075732 CA311813 CA446537 DC416977 NM_001258374 NP_001245303 NM_001258375 NP_001245304 NM_001258376 NP_001245305 NM_021235 NP_067058 NR_047665 NR_047666 |
Function | Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. {ECO:0000269|PubMed:22648170, ECO:0000269|PubMed:9407958}. |
Subcellular Location | Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Nucleus {ECO:0000250}. Membrane, coated pit {ECO:0000250}. Note=Localized to plasma membrane coated pits. {ECO:0000250}. |
Human EPS15R protein fragment - ab127324 from Abcam
|
||||||||||
EPS15L1 / EPS15R Antibody Blocking Peptide - LS-E6907 from LifeSpan Bioscience
|
||||||||||
EPS15L1 / EPS15R Antibody Blocking Peptide - LS-E24551 from LifeSpan Bioscience
|
||||||||||
EPS15R Peptide - P0970 from Novus Biologicals
|
||||||||||
EPS15R Peptide - P0969 from Novus Biologicals
|
||||||||||
EPS15R-Antibody-C-term-Blocking-Peptide - BP2160b from Abgent, a WuXi AppTec company
|
||||||||||
EPS15R-Antibody-N-term-Blocking-Peptide - BP2160a from Abgent, a WuXi AppTec company
|
||||||||||
EPS15L1 fusion protein - Ag15735 from Proteintech Group
|
||||||||||
Recombinant Human EPS15L1, GST-tagged - EPS15L1-12505H from Creative Biomart
|
||||||||||
Recombinant Human Epidermal growth factor receptor substrate 15-like 1(EPS15L1) - CSB-YP871379HU CSB-EP871379HU CSB-BP871379HU CSB-MP871379HU from Cusabio
|
||||||||||
EPS15L1 Protein - abx163945 from Abbexa
|
||||||||||
EPS15R Recombinant Protein Antigen - NBP1-84828PEP from Novus Biologicals
|
||||||||||
EPS15L1 Peptide, Human - M34GP05013H from Creative Peptides
|
||||||||||
Epidermal growth factor receptor substrate 15-like 1 (EPS15L1), partial, Recombinant Protein - MBS1439236 from MyBioSource
|
||||||||||
EPS15R Recombinant Protein Antigen - NBP2-56664PEP from Novus Biologicals
|