SLC27A4

Gene Symbol SLC27A4
Entrez Gene 10999
Alt Symbol ACSVL4, FATP4, IPS
Species Human
Gene Type protein-coding
Description solute carrier family 27 (fatty acid transporter), member 4
Other Description long-chain fatty acid transport protein 4
Swissprots A8K2F7 Q96G53 Q6P1M0 O95186
Accessions EAW87779 EAW87780 Q6P1M0 AA350218 AF055899 AAD11623 AI478495 AK000722 AK027504 BAG51333 AK074831 BAG52010 AK290222 BAF82911 AK314681 BC004268 AAH04268 BC009959 AAH09959 BC065003 AAH65003 H16504 NM_005094 NP_005085
Function Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Appears to be the principal fatty acid transporter in small intestinal enterocytes. Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (VLCFAs). Indirectly inhibits RPE65 via substrate competition and via production of VLCFA derivatives like lignoceroyl-CoA. Prevents light-induced degeneration of rods and cones (By similarity). {ECO:0000250}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000250}.
Tissue Specificity Expressed at highest levels in brain, testis, colon and kidney. Expressed at medium levels in heart and liver, small intestine and stomach. Expressed at low levels in peripheral leukocytes, bone marrow, skeletal muscle and aorta. Expressed in adipose tissue. {ECO:0000269|PubMed:9878842}.
Top Pathways PPAR signaling pathway, Fat digestion and absorption

Human SLC27A4 / FATP4 full length protein - ab132824 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE analysis of ab132824 stained with Coomassie Blue.

Human SLC27A4 / FATP4 peptide - ab74892 from Abcam

Category Peptide

Recombinant Human FATP4/SLC27A4 Protein - H00010999-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

SLC27A4-Antibody-C-term-Blocking-Peptide - BP13227b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

FATP4 (His Tag) protein - orb171577 from Biorbyt

Category Protein
Prices $323.00, $646.00
Sizes 20 μg, 100 μg
Source Human Cells
Species Human
SDS-PAGE analysis of FATP4 (His Tag) protein

FATP4 Blocking Peptide - 33R-10696 from Fitzgerald

Category Peptide
Prices $145.00
Sizes 50 µg

SLC27A4 Blocking Peptide - 33R-10148 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

SLC27A4 / FATP4 - H00010999-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

SLC27A4 / FATP4 - H00010999-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

SLC27A4 fusion protein - Ag1490 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human SLC27A4, GST-tagged - SLC27A4-2737H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human SLC27A4, His-tagged - SLC27A4-394H from Creative Biomart

Category Protein
Source Human Cells
Species Human

Human SLC27A4 / FATP4 Protein (His Tag) - 13861-H07H-20 from Sino Biological

Category Protein
Source Human Cells
Species Human

SLC27A4 Protein - abx163893 from Abbexa

Category Protein
Species Human

SLC27A4 Peptide, Human - M34GP14468H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Human SLC27A4 / FATP4 Protein (His Tag) - 13861-H07H from ABclonal

Category Protein
Prices $138.00, $348.00
Sizes 20 µg, 100 µg
Source Human Cells
Species Human

Long-chain fatty acid transport protein 4 (SLC27A4), Recombinant Protein - MBS7030034 from MyBioSource

Category Protein
Prices $1,435.00, $2,420.00, $3,625.00
Sizes 10 µg, 50 µg, 100 µg
Source Cell Free Expression
Species Human
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