SS18

Gene Symbol SS18
Entrez Gene 6760
Alt Symbol SSXT, SYT
Species Human
Gene Type protein-coding
Description synovial sarcoma translocation, chromosome 18
Other Description protein SSXT|synovial sarcoma translocated to X chromosome protein|synovial sarcoma, translocated to X chromosome
Swissprots Q15532 B0YJ95 Q4VAX1 Q9BXC6
Accessions ACA06073 EAX01209 EAX01210 EAX01211 EAX01212 EAX01213 Q15532 AF161377 AAF28937 AF244972 AAM00188 AF343880 AAK21314 AK289510 BAF82199 AK296949 BAG59495 AK299082 BAG61146 AK301504 BAG63015 AK304305 BAG65158 AK307923 AK316302 BAH14673 AK316338 BAH14709 AU279615 AW081610 BC096221 AAH96221 BC096222 AAH96222 BC096223 AAH96223 BC096224 AAH96224 CR542088 CAG46885 CR542103 CAG46900 DC378335 EU832762 ACE87773 GQ129305 ACT64439 X79201 CAA55792 XM_005258334 XP_005258391 XM_006722527 XP_006722590 XM_011526145 XP_011524447 XM_011526146 XP_011524448 XM_011526147 XP_011524449 XM_011526148 XP_011524450 XM_011526149 XP_011524451 XM_011526150 XP_011524452 XM_011526151 XP_011524453 XM_011526152 XP_011524454 NM_001007559 NP_001007560 NM_001308201 NP_001295130 NM_005637 NP_005628
Function Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2 function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation. {ECO:0000269|PubMed:15919756}.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Fairly ubiquitously expressed. Expressed in synovial sarcomas and in other human cell lines. The fusion genes SSXT-SSX1 and SSXT-SSX2 are expressed only in synovial sarcomas.
Top Pathways Transcriptional misregulation in cancer

SYT (C-3) - sc-390266 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SYT (C-3): sc-390266. Western blot analysis of SYT expression in F9 whole cell lysate.

SYT (E-5) - sc-374299 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SYT (E-5): sc-374299. Western blot analysis of SYT expression in non-transfected: sc-117752 (A) and human SYT transfected: sc-178011 (B) 293T whole cell lysates.

SYT (D-3) - sc-390615 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SYT (D-3): sc-390615. Western blot analysis of SYT expression in F9 whole cell lysate.

SYT (A-10) - sc-365170 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SYT (A-10): sc-365170. Western blot analysis of SYT expression in IMR-32 whole cell lysate.

SYT (S-15) - sc-32521 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SYT (S-15): sc-32521. Western blot analysis of SYT expression in DT40 (A), IMR-32 (B), Jurkat (C) and K-562 (D) whole cell lysates.

SYT (C-19) - sc-8820 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SYT (C-19): sc-8820. Western blot analysis of SYT expression in non-transfected 293T: sc-117752 (A), human SYT transfected 293T: sc-178011 (B) whole cell lysates and HeLa (C) nuclear extract.

SYT (S-13) - sc-32520 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

SYT (H-80) - sc-28698 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
SYT (H-80): sc-28698. Western blot analysis of SYT expression in non-transfected 293T: sc-117752 (A), human SYT transfected 293T: sc-178011 (B) whole cell lysates and HeLa (C) nuclear extract.

SYT (N-18) - sc-8819 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SYT (N-18): sc-8819. Western blot analysis of SYT expression in non-transfected 293T: sc-117752 (A), human SYT transfected 293T: sc-178011 (B) whole cell lysates and HeLa (C) nuclear extract.

Anti-SS18 antibody - ab179927 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin embedded Human lung epithelium tissue labeling SS18 with ab179927 at 5 µg/ml.

Anti-SS18 antibody - ab89086 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-SS18 antibody (ab89086) at 1 µg/ml + A-431 cell lysate at 50 µg

Anti-SS18 antibody - ab66013 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-SS18 antibody (ab66013) at 1/500 dilutionLane 1 : HepG2 cell extractsLane 2 : COLO205 cell extractsLane 3 : Jurkat cell extractsLane 4 : Jurkat cell extracts with immunising peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-SS18 Antibody (C-Terminus) - LS-C346010 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of SSXT Antibody with human Fetal Kidney lysate.

Anti-SS18 Antibody (aa14-18) - LS-C205102 from LifeSpan Bioscience

Prices $265.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Western blot of extracts from A431 cells using SYT antibody.

Anti-SS18 Antibody (clone 1C8) - LS-C198270 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1C8
Western Blot analysis of SS18 expression in transfected 293T cell line by SS18 monoclonal antibody (M07), clone 1C8.Lane 1: SS18 transfected lysate (Predicted MW: 45.9 KDa).Lane 2: Non-transfected lysate.

Anti-SS18 Antibody (aa1-50) IHC-plus™ - LS-B8030 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SS18 / SYT antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8030 dilution 5 ug/ml.

Anti-SS18 Antibody (Ala7) IHC-plus™ - LS-B9154 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human, Lung endothelium: Formalin-Fixed Paraffin-Embedded (FFPE)

SS18 Antibody - NBP2-31612 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: SS18 Antibody [NBP2-31612] - Staining of human cerebral cortex shows moderate nuclear positivity in neuronal cells.

SS18 Antibody - NBP2-31777 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: SS18 Antibody [NBP2-31777] - Staining of human cerebral cortex shows strong nuclear positivity in neuronal cells and glial cells.

SS18 Antibody - H00006760-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: SS18 Antibody [H00006760-B01P] - Analysis of SS18 expression in A-431.

SS18 Antibody (1C8) - H00006760-M07 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1C8
Western Blot: SS18 Antibody (1C8) [H00006760-M07] - Analysis of SS18 expression in transfected 293T cell line by SS18 monoclonal antibody (M07), clone 1C8. Lane 1: SS18 transfected lysate (Predicted MW: 45.9 KDa). Lane 2: Non-transfected lysate.

Anti-SSXT, N-Terminal antibody produced in rabbit - SAB4502864 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SSXT: <B>Cat. No. SAB4502864</B>: Immunoblotting analysis of extracts from HepG2/Jurkat/COLO205 cells, using Anti-SSXT antibody. The lane on the left was treated with the Anti-SSXT antibody. The lane on the right (negative control) was treated with both Anti-SSXT antibody and the synthesized immunogen peptide.

Anti-SS18 antibody produced in mouse - SAB1406484 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-SS18: <B>Cat. No. SAB1406484</B>: Antibody concentration: 10 μg/mL using HeLa cell.

Anti-SS18 antibody produced in rabbit - HPA055741 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SS18: <B>Cat. No. HPA055741</B>: Immunohistochemical staining of Human colon shows strong nuclear, cytoplasmic and membranous positivity in glandular cells.

Anti-SS18 antibody produced in rabbit - HPA059539 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SS18: <B>Cat. No. HPA059539</B>: Immunohistochemical staining of Human cerebral cortex shows strong nuclear positivity in neuronal cells and glial cells.
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