SS18

Gene Symbol SS18
Entrez Gene 6760
Alt Symbol SSXT, SYT
Species Human
Gene Type protein-coding
Description synovial sarcoma translocation, chromosome 18
Other Description protein SSXT|synovial sarcoma translocated to X chromosome protein|synovial sarcoma, translocated to X chromosome
Swissprots Q15532 B0YJ95 Q4VAX1 Q9BXC6
Accessions ACA06073 EAX01209 EAX01210 EAX01211 EAX01212 EAX01213 Q15532 AF161377 AAF28937 AF244972 AAM00188 AF343880 AAK21314 AK289510 BAF82199 AK296949 BAG59495 AK299082 BAG61146 AK301504 BAG63015 AK304305 BAG65158 AK307923 AK316302 BAH14673 AK316338 BAH14709 AU279615 AW081610 BC096221 AAH96221 BC096222 AAH96222 BC096223 AAH96223 BC096224 AAH96224 CR542088 CAG46885 CR542103 CAG46900 DC378335 EU832762 ACE87773 GQ129305 ACT64439 X79201 CAA55792 XM_005258334 XP_005258391 XM_006722527 XP_006722590 XM_011526145 XP_011524447 XM_011526146 XP_011524448 XM_011526147 XP_011524449 XM_011526148 XP_011524450 XM_011526149 XP_011524451 XM_011526150 XP_011524452 XM_011526151 XP_011524453 XM_011526152 XP_011524454 NM_001007559 NP_001007560 NM_001308201 NP_001295130 NM_005637 NP_005628
Function Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2 function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation. {ECO:0000269|PubMed:15919756}.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Fairly ubiquitously expressed. Expressed in synovial sarcomas and in other human cell lines. The fusion genes SSXT-SSX1 and SSXT-SSX2 are expressed only in synovial sarcomas.
Top Pathways Transcriptional misregulation in cancer

SS18-Over-expression-Lysate - LY16466a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag SS18 (arrow) using his tag antibody. 293T cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SS18 gene‘

SS18 293T Cell Transient Overexpression Lysate(Denatured) - H00006760-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

SS18 293 Cell Lysate - 409956 from ABBIOTEC

Category Cell Lysate
Prices $672.00
Sizes 100 µg
Disease Cancer

SS18 Overexpression Lysate (Native) - NBP2-08819 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg
Western Blot: SS18 Overexpression Lysate (Adult Normal) [NBP2-08819] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SS18.

SYT (h): 293T Lysate - sc-178011 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

SS18 Over-expression Lysate Product - GWB-297625 from Genway Biotech

Category Cell Lysate
Prices $756.00
Sizes 100 µg
Species Human

SS18 Overexpression Lysate (Native) - NBP2-09819 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: SS18 Overexpression Lysate (Adult Normal) [NBP2-09819] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SS18.

SS18 Overexpression Lysate (Native) - NBP2-07721 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg

SS18 Overexpression Lysate (Denatured) - H00006760-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

Panoply™ Human SS18 Knockdown Stable Cell Line - CSC-DC015190 from Creative biogene

Category Cell Line
Species Human

Human SS18 Knockout Cell Line-HeLa - CSC-RT1634 from Creative biogene

Category Cell Line
Species Human

SS18 KO Cell Lysate-HeLa - CLKO-1481 from Creative biogene

Category Cell Lysate
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