Gene Symbol | SOAT1 |
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Entrez Gene | 6646 |
Alt Symbol | ACACT, ACAT, ACAT-1, ACAT1, SOAT, STAT |
Species | Human |
Gene Type | protein-coding |
Description | sterol O-acyltransferase 1 |
Other Description | acyl-coenzyme A:cholesterol acyltransferase 1|sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 |
Swissprots | Q5T0X4 B4DU95 A9Z1V7 P35610 Q8N1E4 A8K3P4 A6NC40 |
Accessions | EAW91043 EAW91044 P35610 AK026611 AK290659 BAF83348 AK294047 BAG57399 AK300551 BAG62257 AK310920 AK316401 BAH14772 AL833625 BC028940 AAH28940 BQ182606 DC344271 DQ891807 ABM82733 DQ894991 ABM85917 L21934 AAC37532 XM_011509911 XP_011508213 XM_011509912 XP_011508214 NM_001252511 NP_001239440 NM_001252512 NP_001239441 NM_003101 NP_003092 NR_045530 |
Function | Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol. Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:16154994}; Multi-pass membrane protein {ECO:0000269|PubMed:16154994}. |
Top Pathways | Steroid biosynthesis |
Human SOAT 1 peptide - ab91082 from Abcam
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Human SOAT 1 protein fragment - ab114700 from Abcam
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SOAT1 Antibody Blocking Peptide - LS-E16600 from LifeSpan Bioscience
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ACAT Partial Recombinant Protein - H00006646-Q01 from Novus Biologicals
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SOAT1 Blocking Peptide - 33R-1527 from Fitzgerald
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ACAT1 / SOAT1 - H00006646-Q01-10 from Acris Antibodies
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ACAT1 / SOAT1 - H00006646-Q01-25 from Acris Antibodies
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SOAT1 fusion protein - Ag3944 from Proteintech Group
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Recombinant Human SOAT1 - SOAT1-31430TH from Creative Biomart
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Recombinant Human SOAT1, GST-tagged - SOAT1-2868H from Creative Biomart
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SOAT1 (1-125) - sc-4495 WB from Santa Cruz Biotechnology
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ACAT Protein - NBP2-32052PEP from Novus Biologicals
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SOAT1 Peptide, Human - M34GP14871H from Creative Peptides
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SOAT1/ACAT1 (163-171) - N07010 from Creative Peptides
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Sterol O-acyltransferase 1 (SOAT1), Recombinant Protein - MBS960628 from MyBioSource
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Sterol O-acyltransferase 1 (SOAT1), Recombinant Protein - MBS7030195 from MyBioSource
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