PABPC4

Gene Symbol PABPC4
Entrez Gene 8761
Alt Symbol APP-1, APP1, PABP4, iPABP
Species Human
Gene Type protein-coding
Description poly(A) binding protein, cytoplasmic 4 (inducible form)
Other Description PABP-4|activated-platelet protein 1|inducible poly(A)-binding protein|poly(A)-binding protein 4|polyadenylate-binding protein 4
Swissprots Q6P0N3 B1ANQ8 Q13310 Q4VC03
Accessions EAX07261 EAX07262 EAX07263 EAX07264 EAX07265 EAX07266 EAX07267 EAX07268 Q13310 AB208962 BAD92199 AK091110 AK125926 AK222917 BAD96637 BC029969 BC065540 AAH65540 BC071591 AAH71591 BC094755 AAH94755 BC106908 AAI06909 BC118568 AAI18569 D12799 BAA02244 DB455681 U33818 AAC50350 U75686 AAB97309 NM_001135653 NP_001129125 NM_001135654 NP_001129126 NM_003819 NP_003810
Function Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:17289661}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Tissue Specificity Expressed at low levels in resting normal T cells; following T-cell activation, however, mRNA levels are rapidly up-regulated.
Top Pathways RNA degradation, RNA transport, mRNA surveillance pathway

Anti-PABPC4 antibody - ab66897 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PABPC4 antibody (ab66897) at 1.25 µg/mlLane 1 : Molecular weight markersLane 2 : HepG2 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-PABPC4 antibody - ab101492 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab101492 at 1/250 dilution staining PABPC4 in a Formalin-fixed, paraffin-embedded section of Human ovarian carcinoma by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Detection utilised DAB.

Anti-PABPC4 antibody - ab169589 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-PABPC4 antibody (ab169589) at 1/500 dilutionLane 1 : PABPC4-transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-PABPC4 antibody - ab130719 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-PABPC4 antibody (ab130719) at 1/100 dilution + U937 cell lysate at 35 µg

Anti-PABPC4 antibody - ab76763 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PABPC4 Antibody (Internal) - LS-C144926 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PABPC4 Antibody (aa219-247, AP) - LS-C265425 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PABPC4 Antibody (aa219-247, APC) - LS-C265426 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PABPC4 Antibody (aa219-247, Biotin) - LS-C265427 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PABPC4 Antibody (aa219-247, FITC) - LS-C265428 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PABPC4 Antibody (aa219-247, Azide-free, HRP) - LS-C265429 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PABPC4 Antibody (aa219-247, PE) - LS-C265430 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PABPC4 Antibody (aa218-247) - LS-C323749 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PABPC4 Antibody (aa432-481) - LS-C80344 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HepG2 cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.

Anti-PABPC4 Antibody (aa181-230) - LS-C31358 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
PABPC4 antibody LS-C31358 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.

Anti-PABPC4 Antibody (aa219-247) - LS-C158520 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PABPC4 Antibody western blot of U937 cell line lysates (35 ug/lane). The PABPC4 antibody detected the PABPC4 protein (arrow).

Anti-PABPC4 Antibody - LS-C155691 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded CL1-5 xenograft, using PABPC4 antibody antibody at 1:500 dilution.

Anti-PABPC4 Antibody (aa594-644) - LS-C288262 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human PABP4 by Immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-PABP4 used at a dilution of 1:200 (1 ug/ml). Detection: DAB.

Anti-PABPC4 Antibody (aa525-575) - LS-C288264 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human PABP4 by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma (left) and colon carcinoma (right). Antibody: Affinity purified rabbit anti-PABP4 used at a dilution of 1:200 (1 ug/ml). Detection: DAB.

Anti-PABPC4 Antibody - LS-C334410 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using PABPC4 antibody.

Anti-PABPC4 Antibody (aa525-575) - LS-C286775 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Mouse PABP4 by Immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-PABP4 used at a dilution of 1:250.

PABPC4 Antibody - NB100-74593 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PABPC4 Antibody [NB100-74593] - Detection of Human and Mouse PABP4 on HeLa whole cell lysate using NB100-74593. PABP4 was also immunoprecipitated by rabbit anti-PABP4 antibody NB100-74594.

PABPC4 Antibody - NB100-74594 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PABPC4 Antibody [NB100-74594] - Detection of Human and Mouse PABP4 on HeLa whole cell lysate using NB100-74594. PABP4 was also immunoprecipitated by rabbit anti-PABP4 antibody NB100-74593.

PABPC4 Antibody - NBP1-57448 from Novus Biologicals

Prices $139.00, $299.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

PABPC4 Antibody - NBP2-13722 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PABPC4 Antibody [NBP2-13722] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-413
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