| Gene Symbol |
C5AR2
|
| Entrez Gene |
27202
|
| Alt Symbol |
C5L2, GPF77, GPR77
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
complement component 5a receptor 2
|
| Other Description |
C5a anaphylatoxin chemotactic receptor 2|C5a anaphylatoxin chemotactic receptor C5L2|G protein-coupled receptor 77|G protein-coupled receptor C5L2
|
| Swissprots |
Q9P296 B2RA09
|
| Accessions |
AAK12640 AAP23197 CAJ33695 EAW57472 Q9P296 AB038237 BAA95414 AK313994 BAG36706 BC067477 AAH67477 BC067478 AAH67478 BC067479 AAH67479 BC067480 AAH67480 BP370117 DA673976 XM_011526736 XP_011525038 XM_011526737 XP_011525039 NM_001271749 NP_001258678 NM_001271750 NP_001258679 NM_018485 NP_060955
|
| Function |
Receptor for the chemotactic and inflammatory C3a, C4a and C5a anaphylatoxin peptides and also for their dearginated forms ASP/C3adesArg, C4adesArg and C5adesArg respectively. Couples weakly to G(i)-mediated signaling pathways. {ECO:0000269|PubMed:11773063, ECO:0000269|PubMed:15833747, ECO:0000269|PubMed:19615750}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:19615750}; Multi-pass membrane protein {ECO:0000269|PubMed:19615750}.
|
| Tissue Specificity |
Frontal cortex, hippocampus, hypothalamus, pons and liver. {ECO:0000269|PubMed:11090875, ECO:0000269|PubMed:11165367}.
|
![Western Blot: GPR77 Overexpression Lysate (Adult Normal) [NBL1-11292] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GPR77.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7212_GPR77%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11292-img0002.jpg)