Gene Symbol | C5AR2 |
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Entrez Gene | 27202 |
Alt Symbol | C5L2, GPF77, GPR77 |
Species | Human |
Gene Type | protein-coding |
Description | complement component 5a receptor 2 |
Other Description | C5a anaphylatoxin chemotactic receptor 2|C5a anaphylatoxin chemotactic receptor C5L2|G protein-coupled receptor 77|G protein-coupled receptor C5L2 |
Swissprots | Q9P296 B2RA09 |
Accessions | AAK12640 AAP23197 CAJ33695 EAW57472 Q9P296 AB038237 BAA95414 AK313994 BAG36706 BC067477 AAH67477 BC067478 AAH67478 BC067479 AAH67479 BC067480 AAH67480 BP370117 DA673976 XM_011526736 XP_011525038 XM_011526737 XP_011525039 NM_001271749 NP_001258678 NM_001271750 NP_001258679 NM_018485 NP_060955 |
Function | Receptor for the chemotactic and inflammatory C3a, C4a and C5a anaphylatoxin peptides and also for their dearginated forms ASP/C3adesArg, C4adesArg and C5adesArg respectively. Couples weakly to G(i)-mediated signaling pathways. {ECO:0000269|PubMed:11773063, ECO:0000269|PubMed:15833747, ECO:0000269|PubMed:19615750}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:19615750}; Multi-pass membrane protein {ECO:0000269|PubMed:19615750}. |
Tissue Specificity | Frontal cortex, hippocampus, hypothalamus, pons and liver. {ECO:0000269|PubMed:11090875, ECO:0000269|PubMed:11165367}. |
Human GPCR C5L2 full length protein - ab153291 from Abcam
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C5AR2 / GPR77 / C5L2 Antibody Blocking Peptide - LS-E28938 from LifeSpan Bioscience
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C5AR2 / GPR77 / C5L2 Antibody Blocking Peptide - LS-E28942 from LifeSpan Bioscience
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C5AR2 / GPR77 / C5L2 Antibody Blocking Peptide - LS-E28941 from LifeSpan Bioscience
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C5AR2 / GPR77 / C5L2 Antibody Blocking Peptide - LS-E28943 from LifeSpan Bioscience
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Recombinant Human C5L2/GPR77 Protein - H00027202-P01 from Novus Biologicals
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GPR77 / C5L2 - H00027202-G01 from Acris Antibodies
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GPR77 / C5L2 - H00027202-P01 from Acris Antibodies
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GPR77 fusion protein - ag11836 from Proteintech Group
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GPR77 fusion protein - ag12054 from Proteintech Group
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Recombinant Human GPR77, GST-tagged - GPR77-13488H from Creative Biomart
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Recombinant Human C5L2/GPR77 Protein - H00027202-G01 from Novus Biologicals
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C5L2/GPR77 Recombinant Protein Antigen - NBP1-86777PEP from Novus Biologicals
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GPR77-Blocking-Peptide-C-term - BP20046b from Abgent, a WuXi AppTec company
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GPR77 Peptide, Human - M34GP06590H from Creative Peptides
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C5a anaphylatoxin chemotactic receptor C5L2 (GPR77), Recombinant Protein - MBS7016249 from MyBioSource
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Complement C5a des Arg Human, Recombinant Protein - MBS637987 from MyBioSource
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