SARNP

Gene Symbol	SARNP
Entrez Gene	84324
Alt Symbol	CIP29, HCC1, HSPC316, THO1
Species	Human
Gene Type	protein-coding
Description	SAP domain containing ribonucleoprotein
Other Description	SAP domain-containing ribonucleoprotein|cytokine induced protein 29 kDa|cytokine-induced protein of 29 kDa|hepatocellular carcinoma 1|nuclear protein Hcc-1|proliferation associated cytokine-inducible protein CIP29|proliferation-associated cytokine-inducible protein CIP29
Swissprots	A8K393 P82979 Q9P066
Accessions	CAC37950 EAW96838 P82979 AF161434 AAF28994 AF486281 AAM09686 AK222719 AK290508 BAF83197 BC007099 AAH07099 BC093051 AAH93051 BI520421 EU446946 ABZ92475 NM_033082 NP_149073 NR_026722 NR_026723
Function	Binds both single-stranded and double-stranded DNA with higher affinity for the single-stranded form. Specifically binds to scaffold/matrix attachment region DNA. Also binds single- stranded RNA. Enhances RNA unwinding activity of DDX39A. May participate in important transcriptional or translational control of cell growth, metabolism and carcinogenesis. Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. {EC
Subcellular Location	Nucleus. Nucleus speckle.
Tissue Specificity	Low expression in spleen, liver, pancreas, testis, thymus, heart, and kidney. Increased levels are seen in hepatocellular carcinoma and pancreatic adenocarcinoma. {ECO:0000269|PubMed:11356193}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active HCC1 full length protein - ab9846 from Abcam Category Protein Prices $110.00, $239.00 Sizes 2 µg, 10 µg Source E. coli

SARNP / Hcc-1 / CIP29 Antibody Blocking Peptide - LS-E4206 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SARNP / Hcc-1 / CIP29 Antibody Blocking Peptide - LS-E18318 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CIP29 Protein - H00084324-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SARNP-Antibody-Center-Blocking-Peptide - BP16466c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human HCC 1 (66 a.a.) protein - orb168479 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

CIP29 Blocking Peptide - 33R-9826 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CIP29 Blocking Peptide - abx064007 from Abbexa Category Peptide Species Human, Mouse, Rat, Monkey

Nuclear protein Hcc-1 - H00084324-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Nuclear protein Hcc-1 - H00084324-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

CIP29 fusion protein - Ag8507 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

CIP29 fusion protein - Ag8526 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

HCC-1 Human - GWB-9E5861 from Genway Biotech Category Protein Prices $75.00, $165.00, $3,230.00 Sizes 2 μg, 10 μg, 1000 μg Species Human

Recombinant Human CIP29, GST-tagged - CIP29-11251H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human SARNP, His-tagged - SARNP-27193TH from Creative Biomart Category Protein Source E. coli

CIP29 Blocking Peptide - CBP2813 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Monkey

SARNP Peptide - BS5663P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human SAP domain-containing ribonucleoprotein(SARNP) - CSB-YP307873HU CSB-EP307873HU CSB-BP307873HU CSB-MP307873HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

HCC-1 Protein (OPPB00290) - OPPB00290 from Aviva Systems Biology Category Protein Prices $215.00 Sizes 2 µg

HCC-1 Recombinant Protein (OPPB00291) - OPPB00291 from Aviva Systems Biology Category Protein Prices $215.00 Sizes 2 µg

CIP29 Protein - abx164879 from Abbexa Category Protein Species Human, Mouse, Rat

Nuclear protein Hcc-1 (full length, N-term HIS tag, transcript variant 1) - TP760051 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

CIP29 Protein - NBP1-91788PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

CIP29 Recombinant Protein Antigen - NBP1-88084PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SARNP Peptide, Human - M34GP13788H from Creative Peptides Category Peptide Source Synthetic. Species Human

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