Gene Symbol | IL13RA1 |
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Entrez Gene | 3597 |
Alt Symbol | CD213A1, IL-13Ra, NR4 |
Species | Human |
Gene Type | protein-coding |
Description | interleukin 13 receptor, alpha 1 |
Other Description | CD213a1 antigen|CT19|IL-13 receptor subunit alpha-1|IL-13R subunit alpha-1|IL-13R-alpha-1|IL13 receptor alpha-1 chain|bB128O4.2.1 (interleukin 13 receptor, alpha 1)|cancer/testis antigen 19|interleukin-13 receptor subunit alpha-1 |
Swissprots | O95646 Q9UDY5 Q99656 Q5JSL4 P78552 |
Accessions | EAW89893 EAW89894 P78552 AB209849 BAD93086 AK123515 BAC85635 AK296958 BAG59502 AK313467 BAG36253 BC009960 AAH09960 BC015768 AAH15768 DQ893454 ABM84380 DQ896296 ABM87295 U81379 AAD00510 U81380 AAD00511 Y09328 CAA70508 Y10659 CAA71669 XM_011531336 XP_011529638 XM_011531337 XP_011529639 NM_001560 NP_001551 |
Function | Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Ubiquitous. Highest levels in heart, liver, skeletal muscle and ovary; lowest levels in brain, lung and kidney. Also found in B-cells, T-cells and endothelial cells. |
Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway |
Active human IL13 receptor alpha 1 protein fragment - ab167745 from Abcam
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Human IL13 receptor alpha 1 protein fragment - ab201717 from Abcam
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Human IL13 receptor alpha 1 protein fragment - ab127289 from Abcam
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IL13RA1 / IL13R Alpha 1 Antibody Blocking Peptide - LS-E4806 from LifeSpan Bioscience
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IL-13 R alpha 1 Recombinant Protein - H00003597-P01 from Novus Biologicals
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Recombinant Human IL-13 R alpha 1 Protein - H00003597-G01 from Novus Biologicals
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IL13RA1-Antibody-N-term-Blocking-Peptide - BP17187a from Abgent, a WuXi AppTec company
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Recombinant Human IL-13 R alpha 1 Fc Chimera, CF - 146-IR-100 from R&D Systems
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Human CA19-9 Antigen Grade Protein (OPMA04176) - OPMA04176 from Aviva Systems Biology
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Human CA19-9 Antigen Grade Protein (OPMA04304) - OPMA04304 from Aviva Systems Biology
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Cancer Ag CA19-9 Calib. Grade Protein (OPMA04377) - OPMA04377 from Aviva Systems Biology
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IL13RA1 protein - 80R-4206 from Fitzgerald
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Human IL13Ra1 Protein - abx067444 from Abbexa
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Human IL13Ra1 Protein - abx067443 from Abbexa
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CD213a1 / IL13RA1 (22-343, His-tag) - AR51888PU-N from Acris Antibodies
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CD213a1 / IL13RA1 (22-343, His-tag) - AR51888PU-S from Acris Antibodies
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CD213a1 / IL13RA1 - H00003597-G01 from Acris Antibodies
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CD213a1 / IL13RA1 - H00003597-P01-10 from Acris Antibodies
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CD213a1 / IL13RA1 - H00003597-P01-25 from Acris Antibodies
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Interleukin 13 Receptor Alpha 1 (IL13Ra1), Human - 20-7877 from ARP American Research Products
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Interleukin 13 Receptor Alpha 1 (IL13Ra1), Human - 20-7878 from ARP American Research Products
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IL13 RA1 Recombinant Protein - 96-425 from ProSci
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IL13RA1 Recombinant Protein (Mass Spec Standard (C13 and N15-labeled)) - 96-430 from ProSci
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Recombinant Human IL13RA1, C13&N15-labeled - IL13RA1-238H from Creative Biomart
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Recombinant Human IL13RA1, His tagged - IL13RA1-2252H from Creative Biomart
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