Cflar

Gene Symbol Cflar
Entrez Gene 12633
Alt Symbol 2310024N18Rik, A430105C05Rik, CLARP, Cash, Casper, ENSMUSG00000072980, FLAME, FLAME-1, Flip, Gm9845, I-FLICE, MRIT, c-Flip
Species Mouse
Gene Type protein-coding
Description CASP8 and FADD-like apoptosis regulator
Other Description FADD-like antiapoptotic molecule 1|MACH-related inducer of toxicity|caspase homolog|caspase-eight-related protein|caspase-like apoptosis regulatory protein|cellular FLICE-like inhibitory protein|inhibitor of FLICE|usurpin
Swissprots O35733 O35707 O35732 D3Z0W6
Accessions CAW32368 CAW32382 EDL00095 EDL00096 EDL00097 EDL00098 O35732 AK009498 AK020765 AK053567 AK142078 AK143812 BAE25546 AK152515 AK161120 AK161220 BAE36245 BB615039 BB856464 BC023121 BC029223 AAH29223 BC085105 AAH85105 BE944648 U97076 AAC53281 Y14041 CAA74368 Y14042 CAA74369 XM_006495635 XP_006495698 XM_011238420 XP_011236722 XM_011238421 XP_011236723 XM_011238422 XP_011236724 XM_011238423 XP_011236725 NM_001289704 NP_001276633 NM_001293804 NP_001280733 NM_001293805 NP_001280734 NM_009805 NP_033935 NM_207653 NP_997536
Function Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity (By similarity). {ECO:0000250}.
Tissue Specificity Highly expressed in heart.
Top Pathways Apoptosis, Chagas disease (American trypanosomiasis), TNF signaling pathway

FLIP L (M-18) - sc-7109 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
FLIP<sub>L</sub> (M-18): sc-7109. Immunoperoxidase staining of formalin fixed, paraffin-embedded human heart muscle tissue showing cytoplasmic staining of myocytes.

Anti-FLIP antibody - ab8422 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-FLIP antibody (ab8422) at 1/500 dilution + NIH3T3 whole cell lysateObserved band size : 55 kDa (why is the actual band size different from the predicted?)

FLIP Antibody - NBP1-77020 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: FLIP Antibody [NBP1-77020] - Analysis of FLIP in K562 cell lysate with FLIP antibody at (A) 1 and (B) 2 ug/ml.

FLIP antibody - GTX74270 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-FLIP antibody used in Immunocytochemistry/ Immunofluorescence. GTX74270

FLIP antibody - orb74333 from Biorbyt

Prices $723.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of NIH/3T3 whole cell lysate using FLIP antibody

Anti -FLIP (CFLAR, CASP8 and FADD-like apoptosis regulator, FLIP) - F4549 from USBiological Life Science

Host Rabbit
Clonality Polyclonal

CFLAR Antibody - abx104103 from Abbexa

Prices $490.00, $490.00, $490.00, $490.00
Sizes 10 μl, 50 μl, 100 μl, 200 μl
Host Rabbit
Clonality Polyclonal

CFLAR / Casper / I-FLICE (C-term) antibody - AP30340PU-N from Acris Antibodies

Prices $340.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunocytochemistry of FLIP in 3T3 cells with AP30340PU-N FLIP antibody at 5 μg/ml.

CFLAR / Casper / I-FLICE antibody - PAB11962 from Acris Antibodies

Prices $500.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

FLIP Antibody - 24027 from Signalway Antibody

Prices $390.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of FLIP in NIH/3T3 whole cell lysate with FLIP antibody at 1:500 dilution.

Anti-CFLAR (C-terminal) polyclonal antibody - CPBT-65143RM from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

CFLAR Antibody - TGB-977 from Reagent Proteins

Prices $348.00, $675.00
Sizes 20.00 µg, 100.00 µg
Host Mouse
Clonality Monoclonal

FLIP Polyclonal Antibody - PA5-19881 from Thermo Fisher Scientific

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunocytochemistry staining of 3T3 cells using a FLIP polyclonal antibody (Product # PA5-19881) at a 5 ug/mL dilution.

FLIP L , Polyclonal Antibody - MBS221590 from MyBioSource

Prices $320.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

FLIP L Antibody - AHP481 from AbD Serotec

Prices $270.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

FLIP (C-Terminus) antibody - pab60140 from Covalab

Host Rabbit
Clonality Polyclonal

Cflar antibody - C-terminal region (OASA08395) - OASA08395 from Aviva Systems Biology

Prices $310.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

anti-c-FLIP antibody - ARG20017 from Arigo Biolaboratories

Host Rabbit
Clonality Polyclonal
ARG20017 anti-c-FLIP antibody WB image Western Blot: 1. HeLa cell lysate 2. Jurkat cell lysate 3. K652 cell lysate stained with anti-FLIP antibody (ARG20017). The immunoaffinity-purified antibody detects 58 kDa FLIPL on SDS-PAGE immunoblots, in samples from human, mouse and rat origins. The antibody recognizes only the FLIPL form.
ARG54399 anti-FLIP gamma / FLIP delta antibody WB image Western Blot: H:HeLa，J:Jurkat; T:THP-1; A:A431; K:K562; N: NIH3T3 stained with ARG54399 anti-FLIP gamma / FLIP delta antibody at 1 μg/ml dilution.

FLIP, Polyclonal Antibody - MBS9407182 from MyBioSource

Prices $320.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-FLIP L C-Terminal antibody produced in rabbit - F9675 from Sigma-Aldrich

Prices $394.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Western blot analysis of FLIP in NIH/3T3 whole cell lysate with Anti-FLIP (<B>Cat. No. F9675</B>) at 1:500 dilution.

FLIP antibody - pab80191 from Covalab

Host Rabbit
Clonality Polyclonal

CFLAR / Casper / I-FLICE (C-term) antibody - TA305960 from Acris Antibodies

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of FLIP in NIH/3T3 whole cell lysate with FLIP antibody at 1:500 dilution.

Anti-Mouse-FLIP-C-Terminal-Antibody- - ABD11325 from Abgent, a WuXi AppTec company

Prices $240.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of NIH/3T3 whole cell lysate probed with Rabbit anti Mouse FLIP
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