Cflar

Gene Symbol Cflar
Entrez Gene 12633
Alt Symbol 2310024N18Rik, A430105C05Rik, CLARP, Cash, Casper, ENSMUSG00000072980, FLAME, FLAME-1, Flip, Gm9845, I-FLICE, MRIT, c-Flip
Species Mouse
Gene Type protein-coding
Description CASP8 and FADD-like apoptosis regulator
Other Description FADD-like antiapoptotic molecule 1|MACH-related inducer of toxicity|caspase homolog|caspase-eight-related protein|caspase-like apoptosis regulatory protein|cellular FLICE-like inhibitory protein|inhibitor of FLICE|usurpin
Swissprots O35733 O35707 O35732 D3Z0W6
Accessions CAW32368 CAW32382 EDL00095 EDL00096 EDL00097 EDL00098 O35732 AK009498 AK020765 AK053567 AK142078 AK143812 BAE25546 AK152515 AK161120 AK161220 BAE36245 BB615039 BB856464 BC023121 BC029223 AAH29223 BC085105 AAH85105 BE944648 U97076 AAC53281 Y14041 CAA74368 Y14042 CAA74369 XM_006495635 XP_006495698 XM_011238420 XP_011236722 XM_011238421 XP_011236723 XM_011238422 XP_011236724 XM_011238423 XP_011236725 NM_001289704 NP_001276633 NM_001293804 NP_001280733 NM_001293805 NP_001280734 NM_009805 NP_033935 NM_207653 NP_997536
Function Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity (By similarity). {ECO:0000250}.
Tissue Specificity Highly expressed in heart.
Top Pathways Apoptosis, Chagas disease (American trypanosomiasis), TNF signaling pathway

FLIP Blocking Peptide - NBP1-77020PEP from Novus Biologicals

Category Peptide
Prices $129.00
Sizes 50 µg

FLIP Peptide - GTX85524-PEP from GeneTex

Category Peptide
Prices $149.00
Sizes 50 μg
Species Mouse

Mouse CFLAR Protein - abx065746 from Abbexa

Category Protein
Source E.coli
Species Mouse

CFLAR / Casper / I-FLICE Control Peptide - AP30340CP-N from Acris Antibodies

Category Peptide
Prices $135.00
Sizes 50 µg

Recombinant CASP8 And FADD Like Apoptosis Regulator (CFLAR) - RPL332Mu01 from Cloud-clone

Category Protein
Source E.coli
Species Mouse

Recombinant Mouse CASP8 and FADD-like apoptosis regulator(Cflar) - CSB-YP005282MO CSB-EP005282MO CSB-BP005282MO CSB-MP005282MO from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Mouse

CASP8 And FADD Like Apoptosis Regulator (CFLAR), Recombinant Protein - MBS2018466 from MyBioSource

Category Protein
Prices $185.00, $390.00, $605.00
Sizes 10 µg, 50 µg, 100 µg
Source Prokaryotic expression
Species Mouse

CASP8 and FADD-like apoptosis regulator (Cflar), Recombinant Protein - MBS1189189 from MyBioSource

Category Protein
Prices $1,150.00, $1,150.00, $1,380.00, $1,380.00, $1,835.00, $1,835.00, $2,300.00, $2,300.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Mouse

CFLAR Recombinant Protein (OPCD02178) - OPCD02178 from Aviva Systems Biology

Category Protein
Source E.coli
Species Mouse
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