FBL

Gene Symbol	FBL
Entrez Gene	2091
Alt Symbol	FIB, FLRN, RNU3IP1
Species	Human
Gene Type	protein-coding
Description	fibrillarin
Other Description	34 kDa nucleolar scleroderma antigen|34-kD nucleolar scleroderma antigen|RNA, U3 small nucleolar interacting protein 1|histone-glutamine methyltransferase|rRNA 2'-O-methyltransferase fibrillarin
Swissprots	Q6IAT5 B5BUE8 O75259 P22087 Q9UPI6
Accessions	AAC28913 AAD15623 EAW56925 P22087 AB451384 BAG70198 AI085380 AK296950 BAG59496 AK308649 BC015218 AAH15218 BC019260 AAH19260 BC019609 AAH19609 BG831506 BT006830 AAP35476 BT020144 AAV38946 CR457069 CAG33350 DQ892314 ABM83240 DQ895517 ABM86443 M59849 AAA52453 X56597 CAA39935 XM_005258651 XP_005258708 XM_011526623 XP_011524925 XM_011548798 XP_011547100 XM_011548799 XP_011547101 NM_001436 NP_001427
Function	S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing by catalyzing the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ104me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (PubMed:24352239). {ECO:0000269|PubMed:24352239}.
Subcellular Location	Nucleus, nucleolus {ECO:0000269|PubMed:14583623, ECO:0000269|PubMed:2026646, ECO:0000269|PubMed:2414294, ECO:0000269|PubMed:24352239}. Note=Fibrillar region of the nucleolus.
Top Pathways	Ribosome biogenesis in eukaryotes

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Anti-Fibrillarin Antibody ELISA Kit - abx053424 from Abbexa Category ELISA Kit

Anti-fibrillarin antibody, AFA/snoRNP/U3RNP, Human, ELISA Kit - CSB-E09697h from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Anti-fibrillarin antibody, AFA/snoRNP/U3RNP, Human, ELISA Kit - E01A2071 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Anti-Fibrillarin Antibody, AFA/snoRNP/U3RNP, Human, ELISA Kit - YHB0255Hu from ARP American Research Products Category ELISA Kit

Fibrillarin, FBL, Human, ELISA Kit - E-EL-H2108 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.938 Range 1.563-100ng/mL

Fibrillarin, Human, ELISA Kit - E01F0054 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Fibrillarin, FBL, Mouse, ELISA Kit - E-EL-M0492 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Fibrillarin, FBL, Rabbit, ELISA Kit - E-EL-RB0901 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Fibrillarin, FBL, Chicken, ELISA Kit - E-EL-Ch0221 from ARP American Research Products Category ELISA Kit Prices $445.50 Sizes 96 t

Fibrillarin, FBL, Porcine, ELISA Kit - E-EL-P1769 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Fibrillarin, FBL, Sheep, ELISA Kit - E-EL-S0714 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Fibrillarin, FBL, Monkey, ELISA Kit - E-EL-MK1838 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human FBL ELISA Kit - HF0061 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine FBL ELISA Kit - AF0061 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

FBL, ELISA Kit - MBS2512385 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.375ng/mL Range 0.625-40ng/mL

FBL, ELISA Kit - MBS2503799 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.938ng/mL Range 1.563-100ng/mL

FBL, ELISA Kit - MBS2510238 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.938ng/mL Range 1.563-100ng/mL

FBL, ELISA Kit - MBS2512573 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.938ng/mL Range 1.563-100ng/mL

FBL, ELISA Kit - MBS2510822 from MyBioSource Category ELISA Kit Prices $490.00, $585.00, $2,475.00, $4,360.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.469ng/mL Range 0.781-50ng/mL

FBL, ELISA Kit - MBS2503912 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.938ng/mL Range 1.563-100ng/mL

FBL, ELISA Kit - MBS2512362 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

Fibrillarin, ELISA Kit - MBS748679 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fibrillarin, ELISA Kit - MBS030344 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fibrillarin, ELISA Kit - MBS038280 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fibrillarin, ELISA Kit - MBS012177 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Search more