| Gene Symbol |
SPRY2
|
| Entrez Gene |
10253
|
| Alt Symbol |
hSPRY2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
sprouty homolog 2 (Drosophila)
|
| Other Description |
protein sprouty homolog 2|sprouty 2|spry-2
|
| Swissprots |
B2R9J9 Q5T6Z7 O43597
|
| Accessions |
EAW80601 O43597 AF039843 AAC04258 AK313810 BAG36546 AL713749 CAD28524 AM392994 CAL37872 AM393598 CAL38475 BC004205 AAH04205 BC015745 AAH15745 BX648582 XM_005266217 XP_005266274 XM_006719753 XP_006719816 XM_011534867 XP_011533169 NM_005842 NP_005833
|
| Function |
May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis. {ECO:0000269|PubMed:10887178}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10887178}. Cell projection, ruffle membrane {ECO:0000269|PubMed:10887178}. Note=Associated with microtubules in unstimulated cells but is translocated to the membrane ruffles in cells stimulated ith EGF (epidermal growth factor).
|
| Top Pathways |
Jak-STAT signaling pathway, MicroRNAs in cancer
|
![Western Blot: Sprouty 2 Overexpression Lysate (Adult Normal) [NBL1-16435] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Sprouty 2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/8115_Sprouty%25202%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-16435-img0002.jpg)