SPRY2

Gene Symbol SPRY2
Entrez Gene 10253
Alt Symbol hSPRY2
Species Human
Gene Type protein-coding
Description sprouty homolog 2 (Drosophila)
Other Description protein sprouty homolog 2|sprouty 2|spry-2
Swissprots B2R9J9 Q5T6Z7 O43597
Accessions EAW80601 O43597 AF039843 AAC04258 AK313810 BAG36546 AL713749 CAD28524 AM392994 CAL37872 AM393598 CAL38475 BC004205 AAH04205 BC015745 AAH15745 BX648582 XM_005266217 XP_005266274 XM_006719753 XP_006719816 XM_011534867 XP_011533169 NM_005842 NP_005833
Function May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis. {ECO:0000269|PubMed:10887178}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10887178}. Cell projection, ruffle membrane {ECO:0000269|PubMed:10887178}. Note=Associated with microtubules in unstimulated cells but is translocated to the membrane ruffles in cells stimulated ith EGF (epidermal growth factor).
Top Pathways Jak-STAT signaling pathway, MicroRNAs in cancer

Spry2 Antibody - 13264 from Cell Signaling Technology

Prices $239.00
Sizes 100 µl (10885)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using Spry2 Antibody.

Sprouty 2 (H-120) - sc-30049 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Sprouty 2 (H-120): sc-30049. Western blot analysis of Sprouty 2 expression in C32 whole cell lysate.

Sprouty 2 (L-16) - sc-18601 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Sprouty 2 (L-16): sc-18601. Western blot analysis of Sprouty 2 expression in C32 whole cell lysate.

Sprouty 2 (N-19) - sc-18600 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Sprouty 2 (N-19): sc-18600. Western blot analysis of Sprouty 2 expression in non-transfected: sc-117752 (A) and human Sprouty 2 transfected: sc-129840 (B) 293T whole cell lysates.

Sprouty 2 (SQ-5) - sc-100862 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Sprouty 2 (SQ-5): sc-100862. Western blot analysis of Sprouty 2 expression in C32 whole cell lysate.

Anti-Sprouty 2 antibody - ab60719 from Abcam

Prices $394.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-Sprouty 2 antibody (ab60719) at 1 µg/ml + C32 cell lysate at 25 µg

Anti-Sprouty 2 antibody - ab85670 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Sprouty 2 antibody (ab85670) at 1 µg/mlLane 1 : Brain (Human) Tissue Lysate - adult normal tissue (ab29466)Lane 2 : Lung (Human) Tissue LysateLane 3 : Heart (Human) Tissue Lysate - adult normal tissue (ab29431)Lane 4 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell Lysate Lane 5 : Caco 2 (Human colonic carcinoma cell line) Whole Cell Lysate Lane 6 : SW480 (Human colon adenocarcinoma cell line) Whole Cell Lysate Lysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Sprouty 2 antibody - ab191284 from Abcam

Prices $384.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human kidney tissue labeling Sprouty 2 with ab191284 at 10 µg/ml.

Anti-Sprouty 2 antibody [EPR4318(2)(B)] - ab180527 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4318(2)(B)

Anti-Sprouty 2 antibody - Aminoterminal end - ab50317 from Abcam

Prices $401.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab50317 staining Sprouty 2 in Mouse 8-cell stage pre-implantation embryo by ICC/IF (Immunocytochemistry/immunofluorescence). Cells were fixed with paraformaldehyde, permeabilized with 0.5% Triton X-100 in 1x PBS and blocked with 3% BSA for 4 hours 30 minutes at 4°C. Samples were incubated with primary antibody (1/300 in 1 x PBS + 3% BSA + 0.15% Tween-20) for 16 hours at 4°C. An Alexa Fluor® 555-conjugated Goat anti-rabbit IgG polyclonal (1/1000) was used as the secondary antibody.The image of an 8-cell stage pre-implantation Mouse embryo that was injected with wtSpry2 (N-terminally tagged with YFP) mRNA at 2-cell stage (in green) and stained with anti-Spry2 antibody (ab50317) (in red). Nuclei are stained with DAPI (in blue).See Abreview

Anti-SPRY2 / Sprouty 2 Antibody - LS-C10336 from LifeSpan Bioscience

Prices $515.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SPRY2 / Sprouty 2 Antibody (aa26-39) - LS-C10337 from LifeSpan Bioscience

Prices $455.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal

Anti-SPRY2 / Sprouty 2 Antibody (aa1-175) - LS-C132179 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-SPRY2 / Sprouty 2 Antibody (aa5-35, APC) - LS-C270257 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SPRY2 / Sprouty 2 Antibody (aa5-35, AP) - LS-C270256 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SPRY2 / Sprouty 2 Antibody (aa5-35, Biotin) - LS-C270258 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SPRY2 / Sprouty 2 Antibody (aa5-35, FITC) - LS-C270259 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SPRY2 / Sprouty 2 Antibody (aa5-35, Azide-free, HRP) - LS-C270260 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SPRY2 / Sprouty 2 Antibody (aa5-35, PE) - LS-C270261 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SPRY2 / Sprouty 2 Antibody (aa75-125) - LS-C290200 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SPRY2 / Sprouty 2 Antibody (aa265-315) - LS-C290202 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SPRY2 / Sprouty 2 Antibody (N-Terminus) - LS-C81563 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HepG2 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-SPRY2 / Sprouty 2 Antibody (aa116-305, Biotin) - LS-C300692 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SPRY2 / Sprouty 2 Antibody (aa116-305, Biotin) - LS-C300693 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SPRY2 / Sprouty 2 Antibody (aa116-304, Biotin) - LS-C300695 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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