TNS2

Gene Symbol TNS2
Entrez Gene 23371
Alt Symbol C1-TEN, C1TEN, TENC1
Species Human
Gene Type protein-coding
Description tensin 2
Other Description C1 domain-containing phosphatase and tensin homolog|tensin like C1 domain containing phosphatase (tensin 2)|tensin like C1 domain-containing phosphatase|tensin-2|tensin-like C1 domain-containing phosphatase
Swissprots A2VDI8 Q7Z5T9 A2VDF2 Q9UPS7 Q8NFG0 Q9NT29 Q8NFF9 Q76MW6 A2VDF3 A5PKY4 Q96P25 Q63HR2 Q2NL80
Accessions EAW96658 EAW96659 EAW96660 Q63HR2 AB028998 BAA83027 AF417490 AAL14641 AF518728 AAN03866 AF518729 AAM74225 AK131320 BAG54765 AK172747 BAD18734 AL137564 CAB70815 BC054099 AAH54099 BC110854 AAI10855 BC129828 AAI29829 BC129829 AAI29830 BC131503 AAI31504 BC142668 AAI42669 BC142712 AAI42713 BC150259 AAI50260 BX647126 CAH56176 CA306931 CR936725 XM_006719302 XP_006719365 XM_006719303 XP_006719366 XM_006719304 XP_006719367 XM_011538079 XP_011536381 NM_015319 NP_056134 NM_170754 NP_736610 NM_198316 NP_938072
Function Regulates cell motility and proliferation. May have phosphatase activity. Reduces AKT1 phosphorylation. Lowers AKT1 kinase activity and interferes with AKT1 signaling. {ECO:0000269|PubMed:15817639}.
Subcellular Location Cell junction, focal adhesion {ECO:0000269|PubMed:11792844}. Cell membrane {ECO:0000269|PubMed:11792844}; Peripheral membrane protein {ECO:0000269|PubMed:11792844}; Cytoplasmic side {ECO:0000269|PubMed:11792844}. Note=Detected at the end of actin stress fibers.
Tissue Specificity Detected in heart, kidney, brain, thymus, spleen, liver, placenta, lung, skeletal muscle and small intestine. {ECO:0000269|PubMed:11792844, ECO:0000269|PubMed:12470648}.

Tensin 2 Antibody - 11990 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using Tensin 2 Antibody.

Tns2 (N-12) - sc-109094 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-TENC1 (phospho Y483) antibody - ab138414 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-TENC1 (phospho Y483) antibody (ab138414) at 1/500 dilution + K562 cell extract at 30 µg

Anti-TENC1 antibody - ab96381 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-TENC1 antibody (ab96381) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

Anti-TENC1 antibody - ab135945 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-TENC1 antibody (ab135945) at 1/500 dilution + HepG2 cell extracts at 30 µg

Anti-TNS2 / TENC1 Antibody (phospho-Tyr483) - LS-C291528 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TNS1 / Tensin-1 Antibody (phospho-Tyr483) - LS-C178067 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of p-Tensin-2 (Y483) pAb in extracts from K562cells.

Anti-TNS2 / TENC1 Antibody (aa439-488) - LS-C200023 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from HepG2 cells, using Tensin-2 antibody.

Anti-TNS2 / TENC1 Antibody (aa1088-1409) - LS-C186011 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate). A: Hela. 5% SDS PAGE. TENC1 antibody diluted at 1:1000.

TENC1 Antibody - NBP2-13028 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: TENC1 Antibody [NBP2-13028] - Extracts from K562cells.

TENC1 Antibody - NBP1-90698 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Tensin 2 antibody produced in rabbit - SAB4200161 from Sigma-Aldrich

Prices $55.60, $322.00
Sizes 25 µl, 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell lysates of HEK-293T overexpressing human Tensin 2 (lanes 1,2) and HEK-293T non-transfected (lane 3) were separated on SDS-PAGE, blotted with Anti-Tensin 2 (<B>Cat. No. SAB4200161</B>), and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody: 0.5 μg/mL <BR/>2. Antibody: 0.5 μg/mL + Tensin 2 immunizing peptide (human, 464-480) <BR/>3. Antibody: 0.5 μg/mL

Anti-Tensin 2 (C-terminal) antibody produced in rabbit - SAB4200268 from Sigma-Aldrich

Prices $360.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell lysates of HEK293-T overexpressing human tensin 2 (lanes 1,3), HEK293-T non-transfected (lane 2), were separated on SDS-PAGE, blotted with Anti-Tensin 2 (C-terminal) (<B>Cat. No. SAB4200268</B>), and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody: 1.5 μg/mL <BR/>2. Antibody: 1.5 μg/mL <BR/>3. Antibody: 1.5 μg/mL + immunizing tensin 2 peptide

Anti-TENC1 antibody produced in rabbit - HPA034659 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-TENC1: <B>Cat. No. HPA034659</B>: Immunohistochemical staining of human liver shows moderate cytoplasmic positivity in hepatocytes.

Anti-Tensin 2 (N-terminal) antibody produced in rabbit - SAB4200269 from Sigma-Aldrich

Prices $360.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Cytoplasmic and membrane localization of tensin 2 in NIH3T3 cells overexpressing human tensin 2. Fixed cells were stained with 1 μg/mL Anti-Tensin 2 (N-terminal) (<B>Cat. No. SAB4200269</B>), followed by Goat Anti-Rabbit IgG, Cy3 conjugate (×40 magnification). Nuclear staining with DAPI.

Tensin-2 Antibody (Phospho-Tyr483) (OAAF05467) - OAAF05467 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Tensin-2 Antibody (OAAF05987) - OAAF05987 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

TENC1 antibody - orb73391 from Biorbyt

Prices $723.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal
Western Blot analysis of A:Hela whole cell lysate using TENC1 antibody

TENC1 antibody - 70R-13214 from Fitzgerald

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TENC1 antibody (OAGA00705) - OAGA00705 from Aviva Systems Biology

Prices $340.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TENC1 antibody - orb41473 from Biorbyt

Prices $357.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal

Tensin-2 / TNS2 antibody - PAB8498 from Acris Antibodies

Prices $760.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Imunohistochemical analysis of mouse kidney tissue, using TENC1 polyclonal antibody ( Cat # PAB8498 ) .

Rabbit Anti-Human TENC1, C-term - 107-10786 from RayBiotech

Host Rabbit

Anti-Phospho-Tensin-2 (Y483) antibody - STJ90428 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal

TENC1-Specific antibody - 20055-1-AP from Proteintech Group

Host Rabbit
Clonality Polyclonal
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