USP21

Gene Symbol	USP21
Entrez Gene	27005
Alt Symbol	USP16, USP23
Species	Human
Gene Type	protein-coding
Description	ubiquitin specific peptidase 21
Other Description	NEDD8-specific protease|deubiquitinating enzyme 21|ubiquitin carboxyl-terminal hydrolase 21|ubiquitin specific protease 21|ubiquitin thioesterase 21|ubiquitin thiolesterase 21|ubiquitin-specific processing protease 21|ubiquitin-specific protease 16|ubiquitin-specific-processing protease 21
Swissprots	Q9NYN4 Q5BKT5 Q9HBS2 Q9BTV1 Q5VTW9 Q59H60 Q9UK80 Q5VTX0
Accessions	CCQ43414 EAW52642 EAW52643 EAW52644 EAW52645 Q9UK80 AB208899 BAD92136 AF177758 AAD54321 AF217979 AAG17222 AF233442 AAF61308 AI038040 AK292319 BAF85008 AK310326 AL157417 CAB75649 BC003130 AAH03130 BC090946 AAH90946 BC136291 AAI36292 BI463191 BI755746 BM742944 N76159 T77123 XM_006711274 XP_006711337 XM_011509412 XP_011507714 XM_011509413 XP_011507715 XM_011509414 XP_011507716 NM_001014443 NP_001014443 NM_012475 NP_036607
Function	Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di- and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination (By similarity). Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates. {ECO:0000250, ECO:0000269|PubMed:10799498}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:21888622}. Nucleus {ECO:0000269|PubMed:21888622}.
Tissue Specificity	Highly expressed in heart, pancreas and skeletal muscle. Also expressed in brain, placenta, liver and kidney, and at very low level in lung. {ECO:0000269|PubMed:10799498}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human USP21 full length protein - ab162052 from Abcam Category Protein Source Wheat germ Species Human

Human USP21 protein fragment - ab162053 from Abcam Category Protein Source Wheat germ Species Human

USP21 Antibody Blocking Peptide - LS-E6825 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

USP21 Antibody Blocking Peptide - LS-E19597 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

USP21 Antibody Blocking Peptide - LS-E26766 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

USP21 Antibody Blocking Peptide - LS-E6896 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human USP21 Protein - H00027005-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human USP21 Protein - H00027005-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

USP21 Peptide - P0187 from Novus Biologicals Category Peptide Species Human

USP21 Peptide - P0946 from Novus Biologicals Category Peptide Species Human

USP21 Peptide - P0835 from Novus Biologicals Category Peptide Species Human

USP21-Antibody-N-term-Blocking-Peptide - BP1069a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

USP21-Antibody-N-term-P31-Blocking-Peptide - BP2147b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

USP21-Antibody-C-term-Blocking-Peptide - BP2147a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

USP21-Antibody-Center-Blocking-Peptide - BP2041a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

USP21 blocking peptide - GTX88684-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Rat, Bovine

USP21 Peptide - AC21-1602-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

USP21 - H00027005-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

USP21 - H00027005-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

USP21 - H00027005-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

USP21 - H00027005-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

USP21 Peptide - 46-920P from ProSci Category Peptide

USP21 fusion protein - Ag12234 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

USP21 fusion protein - ag12316 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Ubiquitin carboxyl-terminal hydrolase 21(USP21) - CSB-YP891945HU CSB-EP891945HU CSB-BP891945HU CSB-MP891945HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

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