USP21

Gene Symbol USP21
Entrez Gene 27005
Alt Symbol USP16, USP23
Species Human
Gene Type protein-coding
Description ubiquitin specific peptidase 21
Other Description NEDD8-specific protease|deubiquitinating enzyme 21|ubiquitin carboxyl-terminal hydrolase 21|ubiquitin specific protease 21|ubiquitin thioesterase 21|ubiquitin thiolesterase 21|ubiquitin-specific processing protease 21|ubiquitin-specific protease 16|ubiquitin-specific-processing protease 21
Swissprots Q9NYN4 Q5BKT5 Q9HBS2 Q9BTV1 Q5VTW9 Q59H60 Q9UK80 Q5VTX0
Accessions CCQ43414 EAW52642 EAW52643 EAW52644 EAW52645 Q9UK80 AB208899 BAD92136 AF177758 AAD54321 AF217979 AAG17222 AF233442 AAF61308 AI038040 AK292319 BAF85008 AK310326 AL157417 CAB75649 BC003130 AAH03130 BC090946 AAH90946 BC136291 AAI36292 BI463191 BI755746 BM742944 N76159 T77123 XM_006711274 XP_006711337 XM_011509412 XP_011507714 XM_011509413 XP_011507715 XM_011509414 XP_011507716 NM_001014443 NP_001014443 NM_012475 NP_036607
Function Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di- and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination (By similarity). Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates. {ECO:0000250, ECO:0000269|PubMed:10799498}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:21888622}. Nucleus {ECO:0000269|PubMed:21888622}.
Tissue Specificity Highly expressed in heart, pancreas and skeletal muscle. Also expressed in brain, placenta, liver and kidney, and at very low level in lung. {ECO:0000269|PubMed:10799498}.

USP21 CRISPR/Cas9 KO Plasmid (h) - sc-404690 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP21 HDR Plasmid (h) - sc-404690-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP21 Double Nickase Plasmid (h) - sc-404690-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP21 Double Nickase Plasmid (h2) - sc-404690-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP21 CRISPR Activation Plasmid (h) - sc-404690-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP21 CRISPR Activation Plasmid (h2) - sc-404690-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP21 Lentiviral Activation Particles (h) - sc-404690-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP21 Lentiviral Activation Particles (h2) - sc-404690-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP21 siRNA (h) - sc-76825 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

USP21 shRNA Plasmid (h) - sc-76825-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

USP21 shRNA (h) Lentiviral Particles - sc-76825-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

USP21 RNAi - H00027005-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

USP21 RNAi - H00027005-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU098221 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22570 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22570 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02007 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02007

USP21 siRNA (Human) - CRH8918 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

USP21 - MBS8215775 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human USP21(NM_001014443.2) - SHL117448 from Creative biogene

Category siRNA
Species Reactivities Human

Human USP21 siRNA - orb269420 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

USP21 shRNA Plasmid (Human) - CHH8918 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

USP21 miRNA 3'UTR clone - MiUTR1H-11053 from Creative biogene

Species Reactivities Human

USP21 miRNA 3'UTR clone - MiUTR3H-07047 from Creative biogene

Species Reactivities Human
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