Gene Symbol | ATP11B |
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Entrez Gene | 23200 |
Alt Symbol | ATPIF, ATPIR |
Species | Human |
Gene Type | protein-coding |
Description | ATPase, class VI, type 11B |
Other Description | ATPase IR|P4-ATPase flippase complex alpha subunit ATP11B|probable phospholipid-transporting ATPase IF|truncated ATPase 11B protein |
Swissprots | Q9UKK7 Q9Y2G3 Q96FN1 |
Accessions | EAW78344 EAW78345 EAW78346 EAW78347 Q9Y2G3 AB023173 BAA76800 AF156548 AAF09446 AK093727 BAG52754 AK296750 BAG59333 AK304855 BAG65593 AL133061 CAB61385 BC010630 AAH10630 BC033880 AAH33880 BC042180 AAH42180 BC148558 AAI48559 BF372979 BI861412 BU431705 BX489704 BX537779 CAD97838 DQ925668 ABL59895 DR000074 XM_005247241 XP_005247298 XM_005247243 XP_005247300 XM_011512593 XP_011510895 XM_011512594 XP_011510896 XM_011512595 XP_011510897 XM_011512596 XP_011510898 XM_011512597 XP_011510899 XM_011512598 XP_011510900 NM_014616 NP_055431 |
Function | Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable). Involved in regulation of sensitivity to cisplatin; may contribute to secretory vesicle transport of cisplatin from Golgi to plasma membrane. {ECO:0000269|PubMed:23585472, ECO:0000305}. |
Subcellular Location | Recycling endosome membrane; Multi-pass membrane protein. Early endosome. Endoplasmic reticulum. Golgi apparatus, trans-Golgi network. Note=Exit from the endoplasmic reticulum requires the presence of TMEM30A, but not TMEM30B. In the presence of TMEM30A, mainly located in recycling endosomes. |
ATP11B (H-77) - sc-368515 from Santa Cruz Biotechnology
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ATP11B (N-14) - sc-102333 from Santa Cruz Biotechnology
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ATP11B (P-18) - sc-102334 from Santa Cruz Biotechnology
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Anti-ATP11B antibody - ab105377 from Abcam
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Anti-ATP11B antibody - ab117580 from Abcam
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Anti-ATP11B antibody - ab176976 from Abcam
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Anti-ATP11B antibody - ab82640 from Abcam
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Anti-ATP11B antibody - ab57392 from Abcam
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Anti-ATP11B Antibody (aa1087-1178) - LS-C306435 from LifeSpan Bioscience
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Anti-ATP11B Antibody (aa144-193) - LS-C80981 from LifeSpan Bioscience
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Anti-ATP11B Antibody (N-Terminus) IHC-plus™ - LS-B5488 from LifeSpan Bioscience
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ATP11B Antibody - NBP1-59962 from Novus Biologicals
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ATP11B Antibody - NBP1-77190 from Novus Biologicals
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ATP11B Antibody - NBP1-88900 from Novus Biologicals
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ATP11B Antibody (4H8) - H00023200-M01 from Novus Biologicals
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ATP11B Antibody - H00023200-A01 from Novus Biologicals
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Anti-ATP11B antibody produced in rabbit - HPA036237 from Sigma-Aldrich
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Anti-ATP11B antibody produced in rabbit - HPA036238 from Sigma-Aldrich
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Anti-ATP11B antibody produced in rabbit - SAB2100179 from Sigma-Aldrich
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Monoclonal Anti-ATP11B antibody produced in mouse - WH0023200M1 from Sigma-Aldrich
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Anti-ATP11B antibody produced in rabbit - SAB3500528 from Sigma-Aldrich
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ATP11B antibody - N-terminal region (ARP47046_P050) - ARP47046_P050 from Aviva Systems Biology
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ATP11B antibody - GTX85003 from GeneTex
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Anti -ATP11B (ATPIF, Probable Phospholipid-transporting ATPase IF, ATPase Class VI Type11B, ATPIR) - 209652 from USBiological Life Science
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Anti -ATP11B (Probable Phospholipid-transporting ATPase IF, ATPase IR, ATPase Class VIType 11B, ATPIF, ATPIR, KIAA0956) - 123692 from USBiological Life Science
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