ATP11B

Gene Symbol	ATP11B
Entrez Gene	23200
Alt Symbol	ATPIF, ATPIR
Species	Human
Gene Type	protein-coding
Description	ATPase, class VI, type 11B
Other Description	ATPase IR|P4-ATPase flippase complex alpha subunit ATP11B|probable phospholipid-transporting ATPase IF|truncated ATPase 11B protein
Swissprots	Q9UKK7 Q9Y2G3 Q96FN1
Accessions	EAW78344 EAW78345 EAW78346 EAW78347 Q9Y2G3 AB023173 BAA76800 AF156548 AAF09446 AK093727 BAG52754 AK296750 BAG59333 AK304855 BAG65593 AL133061 CAB61385 BC010630 AAH10630 BC033880 AAH33880 BC042180 AAH42180 BC148558 AAI48559 BF372979 BI861412 BU431705 BX489704 BX537779 CAD97838 DQ925668 ABL59895 DR000074 XM_005247241 XP_005247298 XM_005247243 XP_005247300 XM_011512593 XP_011510895 XM_011512594 XP_011510896 XM_011512595 XP_011510897 XM_011512596 XP_011510898 XM_011512597 XP_011510899 XM_011512598 XP_011510900 NM_014616 NP_055431
Function	Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable). Involved in regulation of sensitivity to cisplatin; may contribute to secretory vesicle transport of cisplatin from Golgi to plasma membrane. {ECO:0000269|PubMed:23585472, ECO:0000305}.
Subcellular Location	Recycling endosome membrane; Multi-pass membrane protein. Early endosome. Endoplasmic reticulum. Golgi apparatus, trans-Golgi network. Note=Exit from the endoplasmic reticulum requires the presence of TMEM30A, but not TMEM30B. In the presence of TMEM30A, mainly located in recycling endosomes.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ATP11B protein fragment - ab161569 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

ATP11B Antibody Blocking Peptide - LS-E30968 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

ATP11B Antibody Blocking Peptide - LS-E17085 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ATP11B Protein - H00023200-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ATP11B Blocking Peptide - NBP1-77190PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

ATP11B Peptide - GTX85003-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

ATP11B Blocking Peptide - 33R-2011 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ATP11B - H00023200-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ATP11B - H00023200-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ATP11B control peptide - AP26239CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

ATP11B Peptide - 5857P from ProSci Category Peptide Species Human

ATP11B fusion protein - ag4654 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

ATP11B Protein - NBP1-88901PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

ATP11B Protein - NBP1-88900PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

ATP11B Peptide, Human - M34GP01125H from Creative Peptides Category Peptide Source Synthetic. Species Human

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