ATP11B

Gene Symbol	ATP11B
Entrez Gene	23200
Alt Symbol	ATPIF, ATPIR
Species	Human
Gene Type	protein-coding
Description	ATPase, class VI, type 11B
Other Description	ATPase IR|P4-ATPase flippase complex alpha subunit ATP11B|probable phospholipid-transporting ATPase IF|truncated ATPase 11B protein
Swissprots	Q9UKK7 Q9Y2G3 Q96FN1
Accessions	EAW78344 EAW78345 EAW78346 EAW78347 Q9Y2G3 AB023173 BAA76800 AF156548 AAF09446 AK093727 BAG52754 AK296750 BAG59333 AK304855 BAG65593 AL133061 CAB61385 BC010630 AAH10630 BC033880 AAH33880 BC042180 AAH42180 BC148558 AAI48559 BF372979 BI861412 BU431705 BX489704 BX537779 CAD97838 DQ925668 ABL59895 DR000074 XM_005247241 XP_005247298 XM_005247243 XP_005247300 XM_011512593 XP_011510895 XM_011512594 XP_011510896 XM_011512595 XP_011510897 XM_011512596 XP_011510898 XM_011512597 XP_011510899 XM_011512598 XP_011510900 NM_014616 NP_055431
Function	Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable). Involved in regulation of sensitivity to cisplatin; may contribute to secretory vesicle transport of cisplatin from Golgi to plasma membrane. {ECO:0000269|PubMed:23585472, ECO:0000305}.
Subcellular Location	Recycling endosome membrane; Multi-pass membrane protein. Early endosome. Endoplasmic reticulum. Golgi apparatus, trans-Golgi network. Note=Exit from the endoplasmic reticulum requires the presence of TMEM30A, but not TMEM30B. In the presence of TMEM30A, mainly located in recycling endosomes.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ATP11B CRISPR/Cas9 KO Plasmid (h) - sc-411692 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ATP11B HDR Plasmid (h) - sc-411692-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ATP11B Double Nickase Plasmid (h) - sc-411692-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ATP11B Double Nickase Plasmid (h2) - sc-411692-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ATP11B CRISPR Activation Plasmid (h) - sc-411692-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ATP11B CRISPR Activation Plasmid (h2) - sc-411692-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ATP11B Lentiviral Activation Particles (h) - sc-411692-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ATP11B Lentiviral Activation Particles (h2) - sc-411692-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ATP11B siRNA (h) - sc-78522 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ATP11B shRNA Plasmid (h) - sc-78522-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ATP11B shRNA (h) Lentiviral Particles - sc-78522-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ATP11B RNAi - H00008544-R01V from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

ATP11B RNAi - H00023200-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU044701 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3673 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3673 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

ATP11B siRNA (Human) - CRH8080 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ATP11B - MBS8202508 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human ATP11B (NM_014616.2) - SHH242410 from Creative biogene Category siRNA Species Reactivities Human

Human ATP11B siRNA - orb268582 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ATP11B shRNA Plasmid (Human) - CHH8080 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

ATP11B miRNA 3'UTR clone - MiUTR4H-TG00651 from Creative biogene Species Reactivities Human

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