Gene Symbol | DDN |
---|---|
Entrez Gene | 23109 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | dendrin |
Other Description | - |
Swissprots | O94850 |
Accessions | EAW58031 O94850 AB018292 BAA34469 BC039264 BC136398 AAI36399 BC136399 AAI36400 XM_011538055 XP_011536357 NM_015086 NP_055901 |
Function | Promotes apoptosis of kidney glomerular podocytes. Podocytes are highly specialized cells essential to the ultrafiltration of blood, resulting in the extraction of urine and the retention of protein (By similarity). {ECO:0000250}. |
Subcellular Location | Cell projection, dendritic spine membrane; Peripheral membrane protein. Cytoplasm. Endoplasmic reticulum membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Perikaryon {ECO:0000250}. Nucleus {ECO:0000250}. Note=Enriched at the cytoplasmic insertion of the slit diaphragm into the foot process of podocytes and associated with polyribosomes in dendrites. {ECO:0000250}. |
Tissue Specificity | Specifically expressed in brain and kidney. Expressed in kidney glomerular capillary loops (at protein level). {ECO:0000269|PubMed:17251388, ECO:0000269|PubMed:18356187}. |
Recombinant Human Dendrin(DDN) - CSB-YP006592HU CSB-EP006592HU CSB-BP006592HU CSB-MP006592HU from Cusabio
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Dendrin Recombinant Protein Antigen - NBP2-37980PEP from Novus Biologicals
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DDN Peptide, Human - M34GP04126H from Creative Peptides
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Dendrin (DDN), Recombinant Protein - MBS1160487 from MyBioSource
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