| Gene Symbol | ARHGEF16 |
|---|---|
| Entrez Gene | 27237 |
| Alt Symbol | GEF16, NBR |
| Species | Human |
| Gene Type | protein-coding |
| Description | Rho guanine nucleotide exchange factor (GEF) 16 |
| Other Description | Rho guanine exchange factor (GEF) 16|ephexin-4|rho guanine nucleotide exchange factor 16 |
| Swissprots | Q5VV41 Q99434 Q86TF0 |
| Accessions | CCQ43438 EAW71452 EAW71453 Q5VV41 AK091910 AK095984 BAG53186 AK296150 BAG58889 AK310408 BC002681 AAH02681 BC051838 AAH51838 BT007270 AAP35934 D89016 BAA13745 DA539376 DB499586 DQ890637 ABM92254 DQ893813 ABM84739 XM_011541251 XP_011539553 XM_011541252 XP_011539554 XM_011541253 XP_011539555 XM_011541254 XP_011539556 XR_946608 NM_014448 NP_055263 |
| Function | Guanyl-nucleotide exchange factor of the RHOG GTPase stimulating the exchange of RHOG-associated GDP for GTP. May play a role in chemotactic cell migration by mediating the activation of RAC1 by EPHA2. May also activate CDC42 and mediate activation of CDC42 by the viral protein HPV16 E6. {ECO:0000269|PubMed:20679435}. |
| Subcellular Location | Cytoplasm {ECO:0000305}. |
Rho guanine exchange factor (GEF) 16, ELISA Kit - MBS9340475 from MyBioSource
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Human ARHGEF16 ELISA Kit - E033521 from Biobool
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