Gene Symbol | ARHGEF16 |
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Entrez Gene | 27237 |
Alt Symbol | GEF16, NBR |
Species | Human |
Gene Type | protein-coding |
Description | Rho guanine nucleotide exchange factor (GEF) 16 |
Other Description | Rho guanine exchange factor (GEF) 16|ephexin-4|rho guanine nucleotide exchange factor 16 |
Swissprots | Q5VV41 Q99434 Q86TF0 |
Accessions | CCQ43438 EAW71452 EAW71453 Q5VV41 AK091910 AK095984 BAG53186 AK296150 BAG58889 AK310408 BC002681 AAH02681 BC051838 AAH51838 BT007270 AAP35934 D89016 BAA13745 DA539376 DB499586 DQ890637 ABM92254 DQ893813 ABM84739 XM_011541251 XP_011539553 XM_011541252 XP_011539554 XM_011541253 XP_011539555 XM_011541254 XP_011539556 XR_946608 NM_014448 NP_055263 |
Function | Guanyl-nucleotide exchange factor of the RHOG GTPase stimulating the exchange of RHOG-associated GDP for GTP. May play a role in chemotactic cell migration by mediating the activation of RAC1 by EPHA2. May also activate CDC42 and mediate activation of CDC42 by the viral protein HPV16 E6. {ECO:0000269|PubMed:20679435}. |
Subcellular Location | Cytoplasm {ECO:0000305}. |
ARHGEF16 CRISPR/Cas9 KO Plasmid (h) - sc-406929 from Santa Cruz Biotechnology
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ARHGEF16 HDR Plasmid (h) - sc-406929-HDR from Santa Cruz Biotechnology
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ARHGEF16 Double Nickase Plasmid (h) - sc-406929-NIC from Santa Cruz Biotechnology
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ARHGEF16 Double Nickase Plasmid (h2) - sc-406929-NIC-2 from Santa Cruz Biotechnology
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ARHGEF16 CRISPR Activation Plasmid (h) - sc-406929-ACT from Santa Cruz Biotechnology
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ARHGEF16 CRISPR Activation Plasmid (h2) - sc-406929-ACT-2 from Santa Cruz Biotechnology
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ARHGEF16 Lentiviral Activation Particles (h) - sc-406929-LAC from Santa Cruz Biotechnology
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ARHGEF16 Lentiviral Activation Particles (h2) - sc-406929-LAC-2 from Santa Cruz Biotechnology
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ARHGEF16 siRNA (h) - sc-88758 from Santa Cruz Biotechnology
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ARHGEF16 shRNA Plasmid (h) - sc-88758-SH from Santa Cruz Biotechnology
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ARHGEF16 shRNA (h) Lentiviral Particles - sc-88758-V from Santa Cruz Biotechnology
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ARHGEF16 RNAi - H00027237-R01 from Novus Biologicals
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MISSION® esiRNA - EHU119751 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3447 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3447 from Sigma-Aldrich
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ARHGEF16 siRNA (Human) - CRH9030 from Cohesion Biosciences
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ARHGEF16 - MBS8230507 from MyBioSource
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shRNA set against Human ARHGEF16 (NM_014448.3) - SHH239738 from Creative biogene
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ARHGEF16 shRNA Plasmid (Human) - CHH9030 from Cohesion Biosciences
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ARHGEF16 miRNA 3'UTR clone - MiUTR1H-00541 from Creative biogene
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