| Gene Symbol |
ARHGEF16
|
| Entrez Gene |
27237
|
| Alt Symbol |
GEF16, NBR
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Rho guanine nucleotide exchange factor (GEF) 16
|
| Other Description |
Rho guanine exchange factor (GEF) 16|ephexin-4|rho guanine nucleotide exchange factor 16
|
| Swissprots |
Q5VV41 Q99434 Q86TF0
|
| Accessions |
CCQ43438 EAW71452 EAW71453 Q5VV41 AK091910 AK095984 BAG53186 AK296150 BAG58889 AK310408 BC002681 AAH02681 BC051838 AAH51838 BT007270 AAP35934 D89016 BAA13745 DA539376 DB499586 DQ890637 ABM92254 DQ893813 ABM84739 XM_011541251 XP_011539553 XM_011541252 XP_011539554 XM_011541253 XP_011539555 XM_011541254 XP_011539556 XR_946608 NM_014448 NP_055263
|
| Function |
Guanyl-nucleotide exchange factor of the RHOG GTPase stimulating the exchange of RHOG-associated GDP for GTP. May play a role in chemotactic cell migration by mediating the activation of RAC1 by EPHA2. May also activate CDC42 and mediate activation of CDC42 by the viral protein HPV16 E6. {ECO:0000269|PubMed:20679435}.
|
| Subcellular Location |
Cytoplasm {ECO:0000305}.
|
