Gene Symbol | ATL3 |
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Entrez Gene | 25923 |
Alt Symbol | HSN1F |
Species | Human |
Gene Type | protein-coding |
Description | atlastin GTPase 3 |
Other Description | atlastin-3 |
Swissprots | Q8N7W5 Q6DD88 Q9UFL1 Q9H8Q5 |
Accessions | EAW74161 EAW74162 EAW74163 Q6DD88 AK023383 BAB14552 AK090822 AK094227 AK097588 BAC05111 AK301910 BAG63336 AL117600 CAB56010 BC077727 AAH77727 BE710391 BI829120 BX642720 BX648468 CR936784 DB034045 DC394729 XM_006718493 XP_006718556 XM_006718494 XP_006718557 XM_011544902 XP_011543204 NM_001290048 NP_001276977 NM_015459 NP_056274 |
Function | GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis. {ECO:0000269|PubMed:18270207, ECO:0000269|PubMed:19665976}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:18270207, ECO:0000269|PubMed:24459106}; Multi- pass membrane protein {ECO:0000269|PubMed:18270207, ECO:0000269|PubMed:24459106}. Note=Localizes to endoplasmic reticulum tubules and accumulates in punctuate structures corresponding to 3-way junctions, which represent crossing-points at which the tubules build a polygonal network. |
Tissue Specificity | Expressed in the central nervous system and in dorsal root ganglia neurons. Expressed in peripheral tissues (at protein level). {ECO:0000269|PubMed:18270207, ECO:0000269|PubMed:24459106}. |
Human ATL3 full length protein - ab153251 from Abcam
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ATL3 Antibody Blocking Peptide - LS-E23656 from LifeSpan Bioscience
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ATL3 Antibody Blocking Peptide - LS-E7560 from LifeSpan Bioscience
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ATL3 Antibody Blocking Peptide - LS-E17109 from LifeSpan Bioscience
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ATL3 Antibody Blocking Peptide - LS-E17110 from LifeSpan Bioscience
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Recombinant Human Atlastin-3 Protein - H00025923-P01 from Novus Biologicals
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ATL3-Antibody-Center-Blocking-Peptide - BP4715c from Abgent, a WuXi AppTec company
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Human Atlastin GTPase 3 (His Tag) protein - orb179686 from Biorbyt
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ATL3 Blocking Peptide - 33R-1974 from Fitzgerald
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ATL3 Blocking Peptide - 33R-4230 from Fitzgerald
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Atlastin-3 - H00025923-P01-10 from Acris Antibodies
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Atlastin-3 - H00025923-P01-25 from Acris Antibodies
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ATL3 fusion protein - Ag10248 from Proteintech Group
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ATL3 fusion protein - Ag10279 from Proteintech Group
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Recombinant Human ATL3, His-tagged - ATL3-9986H from Creative Biomart
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Human ATL3 / Atlastin GTPase 3 Protein (His Tag) - 15483-H07E-20 from Sino Biological
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Atlastin-3 - TP309658 from Acris Antibodies
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Recombinant Human ATL3 Protein, His-tagged - ATL3-690H from Creative Biomart
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ATL3 Peptide, Human - M34GP01113H from Creative Peptides
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Human ATL3 / Atlastin GTPase 3 Protein (His Tag) - 15483-H07E from ABclonal
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Atlastin-3 Recombinant Protein Antigen - NBP2-56000PEP from Novus Biologicals
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