USP16

Gene Symbol	USP16
Entrez Gene	10600
Alt Symbol	UBP-M, UBPM
Species	Human
Gene Type	protein-coding
Description	ubiquitin specific peptidase 16
Other Description	deubiquitinating enzyme 16|ubiquitin carboxyl-terminal hydrolase 16|ubiquitin specific protease 16|ubiquitin thioesterase 16|ubiquitin thiolesterase 16|ubiquitin-processing protease UBP-M|ubiquitin-specific processing protease 16|ubiquitin-specific-processing protease 16
Swissprots	B4DFV8 Q9H3E6 B3KN13 Q53GP7 Q5VKN8 A8MU43 D3DSD9 B4DY37 Q53HA0 Q8NEL3 Q9Y5T5
Accessions	CAB90432 EAX09927 EAX09928 EAX09929 Q9Y5T5 AF113219 AAG39290 AF126736 AAD20949 AK023247 BAG51175 AK025104 AK025989 AK090776 AK222681 BAD96401 AK222884 BAD96604 AK294284 BAG57569 AK300771 BAG62436 AK302247 BAG63599 AY333928 AAR13293 BC010375 BC030777 AAH30777 BQ637016 CB960929 DQ892395 ABM83321 DQ895610 ABM86536 W57837 NM_001001992 NP_001001992 NM_001032410 NP_001027582 NM_006447 NP_006438
Function	Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T- lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B. {ECO:0000255|HAMAP-Rule:MF_03062, ECO:0000269|PubMed:10077596, ECO:0000269|PubMed:17914355}.
Subcellular Location	Nucleus {ECO:0000305|PubMed:17914355}.
Tissue Specificity	Present in all the tissues examined including fetal brain, lung, liver, kidney, and adult heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:10077596}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human USP16 full length protein - ab161059 from Abcam Category Protein Source Wheat germ Species Human

Human USP16 peptide - ab23059 from Abcam Category Peptide Species Human

USP16 Antibody Blocking Peptide - LS-E4433 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

USP16 Antibody Blocking Peptide - LS-E16705 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

USP16 Antibody Blocking Peptide - LS-E6893 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

USP16 Antibody Blocking Peptide - LS-E6894 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

USP16 Recombinant Protein - H00010600-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

USP16 Peptide - P0942 from Novus Biologicals Category Peptide Species Human

USP16 Peptide - P0941 from Novus Biologicals Category Peptide Species Human

USP16-Antibody-N-term-Blocking-Peptide - BP16746a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

USP16-Antibody-Center-Blocking-Peptide - BP2144c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

USP16-Antibody-N-term-Blocking-Peptide - BP2144a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

USP16 blocking peptide - GTX88265-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Horse, Bovine

USP16 blocking peptide - GTX24853-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Dog, Bovine

USP16 Blocking Peptide - 33R-1726 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

USP16 Peptide - AC21-1600-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

USP16 - H00010600-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

USP16 - H00010600-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

USP16 Peptide - 42-222P from ProSci Category Peptide Prices $175.00 Sizes 100 µg

USP16 fusion protein - Ag5185 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

USP16 fusion protein - Ag4981 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human USP16, His-tagged - USP16-3618H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Ubiquitin carboxyl-terminal hydrolase 16(USP16) ,partial - CSB-YP896915HU CSB-EP896915HU CSB-BP896915HU CSB-MP896915HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

USP16 (transcript variant 1) - TP322609 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

USP16, Peptide - MBS426680 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Horse, Dog, Bovine

Search more