Gene Symbol |
TUBA8
|
Entrez Gene |
51807
|
Alt Symbol |
TUBAL2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
tubulin, alpha 8
|
Other Description |
tubulin alpha chain-like 2|tubulin alpha-8 chain
|
Swissprots |
Q2M3N4 Q9NY65 B3KPW9 B2RCX2
|
Accessions |
EAW57788 EAW57789 Q9NY65 AJ245922 CAB88036 AK056947 BAG51831 AK315316 BAG37719 BC074827 AAH74827 BC104845 AAI04846 BX537702 CAD97815 CR456600 CAG30486 CU013200 CAK54631 CU013488 CAK54930 DA059342 NM_001193414 NP_001180343 NM_018943 NP_061816
|
Function |
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
|
Subcellular Location |
Cytoplasm, cytoskeleton.
|
Tissue Specificity |
Preferentially expressed in heart, skeletal muscle and testis. Expressed at low levels in the developing brain. {ECO:0000269|PubMed:20466094}.
|
Top Pathways |
Gap junction, Pathogenic Escherichia coli infection, Phagosome
|