Gene Symbol | TUBA8 |
---|---|
Entrez Gene | 51807 |
Alt Symbol | TUBAL2 |
Species | Human |
Gene Type | protein-coding |
Description | tubulin, alpha 8 |
Other Description | tubulin alpha chain-like 2|tubulin alpha-8 chain |
Swissprots | Q2M3N4 Q9NY65 B3KPW9 B2RCX2 |
Accessions | EAW57788 EAW57789 Q9NY65 AJ245922 CAB88036 AK056947 BAG51831 AK315316 BAG37719 BC074827 AAH74827 BC104845 AAI04846 BX537702 CAD97815 CR456600 CAG30486 CU013200 CAK54631 CU013488 CAK54930 DA059342 NM_001193414 NP_001180343 NM_018943 NP_061816 |
Function | Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. |
Subcellular Location | Cytoplasm, cytoskeleton. |
Tissue Specificity | Preferentially expressed in heart, skeletal muscle and testis. Expressed at low levels in the developing brain. {ECO:0000269|PubMed:20466094}. |
Top Pathways | Gap junction, Pathogenic Escherichia coli infection, Phagosome |