Gene Symbol | TUBA8 |
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Entrez Gene | 51807 |
Alt Symbol | TUBAL2 |
Species | Human |
Gene Type | protein-coding |
Description | tubulin, alpha 8 |
Other Description | tubulin alpha chain-like 2|tubulin alpha-8 chain |
Swissprots | Q2M3N4 Q9NY65 B3KPW9 B2RCX2 |
Accessions | EAW57788 EAW57789 Q9NY65 AJ245922 CAB88036 AK056947 BAG51831 AK315316 BAG37719 BC074827 AAH74827 BC104845 AAI04846 BX537702 CAD97815 CR456600 CAG30486 CU013200 CAK54631 CU013488 CAK54930 DA059342 NM_001193414 NP_001180343 NM_018943 NP_061816 |
Function | Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. |
Subcellular Location | Cytoplasm, cytoskeleton. |
Tissue Specificity | Preferentially expressed in heart, skeletal muscle and testis. Expressed at low levels in the developing brain. {ECO:0000269|PubMed:20466094}. |
Top Pathways | Gap junction, Pathogenic Escherichia coli infection, Phagosome |
α8 Tubulin CRISPR/Cas9 KO Plasmid (h) - sc-400076 from Santa Cruz Biotechnology
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α8 Tubulin HDR Plasmid (h) - sc-400076-HDR from Santa Cruz Biotechnology
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α8 Tubulin Double Nickase Plasmid (h) - sc-400076-NIC from Santa Cruz Biotechnology
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α8 Tubulin Double Nickase Plasmid (h2) - sc-400076-NIC-2 from Santa Cruz Biotechnology
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α8 Tubulin CRISPR Activation Plasmid (h) - sc-400076-ACT from Santa Cruz Biotechnology
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α8 Tubulin CRISPR Activation Plasmid (h2) - sc-400076-ACT-2 from Santa Cruz Biotechnology
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α8 Tubulin Lentiviral Activation Particles (h) - sc-400076-LAC from Santa Cruz Biotechnology
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α8 Tubulin Lentiviral Activation Particles (h2) - sc-400076-LAC-2 from Santa Cruz Biotechnology
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α8 Tubulin siRNA (h) - sc-105025 from Santa Cruz Biotechnology
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α8 Tubulin shRNA Plasmid (h) - sc-105025-SH from Santa Cruz Biotechnology
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α8 Tubulin shRNA (h) Lentiviral Particles - sc-105025-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN22259 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22259 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04684 from Sigma-Aldrich
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TUBA8 siRNA (Human) - CRH9952 from Cohesion Biosciences
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Tubulin alpha-8 RNAi - H00051807-R01 from Novus Biologicals
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shRNA set against Human TUBA8 (NM_018943.2) - SHH437660 from Creative biogene
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TUBA8 shRNA Plasmid (Human) - CHH9952 from Cohesion Biosciences
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TUBA8 miRNA 3'UTR clone - MiUTR3H-07923 from Creative biogene
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