Gene Symbol | TAAR5 |
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Entrez Gene | 9038 |
Alt Symbol | PNR |
Species | Human |
Gene Type | protein-coding |
Description | trace amine associated receptor 5 |
Other Description | hTaar5|putative neurotransmitter receptor|taR-5|trace amine receptor 5|trace amine-associated receptor 5 |
Swissprots | Q5VUQ3 D8KZS1 Q4VBL1 O14804 Q2M1V1 Q6NTA8 |
Accessions | AAV70123 ACP18682 EAW48025 O14804 AF021818 AAC39581 BC069171 AAH69171 BC095541 AAH95541 BC112209 AAI12210 BC112211 AAI12212 NM_003967 NP_003958 |
Function | Olfactory receptor specific for trimethylamine, a trace amine. Also activated at lower level by dimethylethylamine. Trimethylamine is a bacterial metabolite found in some animal odors, and to humans it is a repulsive odor associated with bad breath and spoiled food. This receptor is probably mediated by the G(s)-class of G-proteins which activate adenylate cyclase. {ECO:0000269|PubMed:23393561}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:23393561}; Multi-pass membrane protein {ECO:0000269|PubMed:23393561}. |
Tissue Specificity | Expressed almost exclusively in skeletal muscle and selected areas of the brain, such amygdala, hippocampus, caudate nucleus, thalamus and hypothalamus. Weak expression is also find in substantia nigra. {ECO:0000269|PubMed:9464258}. |
Top Pathways | Neuroactive ligand-receptor interaction |
Human PNR full length protein - ab160304 from Abcam
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Human PNR peptide - ab39787 from Abcam
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TAAR5 Antibody Blocking Peptide - LS-E28699 from LifeSpan Bioscience
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TAAR5 Antibody Blocking Peptide - LS-E28701 from LifeSpan Bioscience
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TAAR5 Antibody Blocking Peptide - LS-E28704 from LifeSpan Bioscience
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TAAR5 Antibody Blocking Peptide - LS-E28998 from LifeSpan Bioscience
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TAAR5 Antibody Blocking Peptide - LS-E21816 from LifeSpan Bioscience
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TAAR5 Antibody Blocking Peptide - LS-E21815 from LifeSpan Bioscience
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Recombinant Human TAAR5 Protein - H00009038-P01 from Novus Biologicals
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TAAR5 Blocking Peptide - 33R-3668 from Fitzgerald
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TAAR5 Blocking Peptide - 33R-9324 from Fitzgerald
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TAAR5 - H00009038-G01 from Acris Antibodies
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TAAR5 - H00009038-P01 from Acris Antibodies
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TAAR5 fusion protein - ag14925 from Proteintech Group
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Recombinant Human TAAR5, GST-tagged - TAAR5-3092H from Creative Biomart
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TAAR5 Recombinant Protein - H00009038-G01 from Novus Biologicals
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TAAR5 Protein - NBP2-13409PEP from Novus Biologicals
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TAAR5-Blocking-Peptide-C-term - BP21290b from Abgent, a WuXi AppTec company
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TAAR5 Peptide, Human - M34GP15519H from Creative Peptides
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