Gene Symbol | TAAR5 |
---|---|
Entrez Gene | 9038 |
Alt Symbol | PNR |
Species | Human |
Gene Type | protein-coding |
Description | trace amine associated receptor 5 |
Other Description | hTaar5|putative neurotransmitter receptor|taR-5|trace amine receptor 5|trace amine-associated receptor 5 |
Swissprots | Q5VUQ3 D8KZS1 Q4VBL1 O14804 Q2M1V1 Q6NTA8 |
Accessions | AAV70123 ACP18682 EAW48025 O14804 AF021818 AAC39581 BC069171 AAH69171 BC095541 AAH95541 BC112209 AAI12210 BC112211 AAI12212 NM_003967 NP_003958 |
Function | Olfactory receptor specific for trimethylamine, a trace amine. Also activated at lower level by dimethylethylamine. Trimethylamine is a bacterial metabolite found in some animal odors, and to humans it is a repulsive odor associated with bad breath and spoiled food. This receptor is probably mediated by the G(s)-class of G-proteins which activate adenylate cyclase. {ECO:0000269|PubMed:23393561}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:23393561}; Multi-pass membrane protein {ECO:0000269|PubMed:23393561}. |
Tissue Specificity | Expressed almost exclusively in skeletal muscle and selected areas of the brain, such amygdala, hippocampus, caudate nucleus, thalamus and hypothalamus. Weak expression is also find in substantia nigra. {ECO:0000269|PubMed:9464258}. |
Top Pathways | Neuroactive ligand-receptor interaction |
TAAR5 CRISPR/Cas9 KO Plasmid (h) - sc-409205 from Santa Cruz Biotechnology
|
||||||||
TAAR5 HDR Plasmid (h) - sc-409205-HDR from Santa Cruz Biotechnology
|
||||||||
TAAR5 Double Nickase Plasmid (h) - sc-409205-NIC from Santa Cruz Biotechnology
|
||||||||
TAAR5 Double Nickase Plasmid (h2) - sc-409205-NIC-2 from Santa Cruz Biotechnology
|
||||||||
TAAR5 CRISPR Activation Plasmid (h) - sc-409205-ACT from Santa Cruz Biotechnology
|
||||||||
TAAR5 CRISPR Activation Plasmid (h2) - sc-409205-ACT-2 from Santa Cruz Biotechnology
|
||||||||
TAAR5 Lentiviral Activation Particles (h) - sc-409205-LAC from Santa Cruz Biotechnology
|
||||||||
TAAR5 Lentiviral Activation Particles (h2) - sc-409205-LAC-2 from Santa Cruz Biotechnology
|
||||||||
TAAR5 siRNA (h) - sc-61375 from Santa Cruz Biotechnology
|
||||||||
TAAR5 shRNA Plasmid (h) - sc-61375-SH from Santa Cruz Biotechnology
|
||||||||
TAAR5 shRNA (h) Lentiviral Particles - sc-61375-V from Santa Cruz Biotechnology
|
||||||||
TAAR5 RNAi - H00009038-R02 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU132141 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN20940 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20940 from Sigma-Aldrich
|
||||||||
TAAR5 siRNA (Human) - CRH5961 from Cohesion Biosciences
|
||||||||
TAAR5 - MBS8233236 from MyBioSource
|
||||||||
shRNA set against Human TAAR5 (NM_003967.2) - SHH422248 from Creative biogene
|
||||||||
Human TAAR5 siRNA - orb266463 from Biorbyt
|
||||||||
TAAR5 shRNA Plasmid (Human) - CHH5961 from Cohesion Biosciences
|
||||||||
TAAR5 miRNA 3'UTR clone - MiUTR4H-TG08723 from Creative biogene
|