NET1

Gene Symbol NET1
Entrez Gene 10276
Alt Symbol ARHGEF8, NET1A
Species Human
Gene Type protein-coding
Description neuroepithelial cell transforming 1
Other Description Rho guanine nucleotide exchange factor (GEF) 8|guanine nucleotide regulatory protein (oncogene)|neuroepithelial cell-transforming gene 1 protein|neuroepithelioma transforming gene 1|p65 Net1 proto-oncogene protein|small GTP-binding protein regulator
Swissprots Q99903 Q9UEN6 Q7Z628 Q12773 Q96D82
Accessions EAW86445 EAW86446 Q7Z628 AB209852 BAD93089 AJ010046 CAA08974 AK024919 AK294244 BAG57540 AK299335 BAG61338 AK302687 BAG63916 AK304028 BAG64943 AK315566 BAG37941 BC010285 AAH10285 BC053553 AAH53553 BP354878 BQ024592 BU633004 BX537509 CD722646 DA727151 DB177813 DC307907 S82401 AAB37683 U02081 AAB08847 NM_001047160 NP_001040625 NM_005863 NP_005854 NR_073040
Function Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death. {ECO:0000269|PubMed:21373644}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:8649828}.

NET1 (G-4) - sc-271941 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
NET1 (G-4): sc-271941. Western blot analysis of NET1 expression in non-transfected: sc-117752 (A) and human NET1 transfected: sc-116463 (B) 293T whole cell lysates.

NET1 (H-70) - sc-50392 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
NET1 (H-70): sc-50392. Western blot analysis of NET1 expression in non-transfected 293T: sc-117752 (A), human NET1 transfected 293T: sc-113505 (B) and HeLa (C) whole cell lysates.

NET1 (N-17) - sc-6080 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-NET1 antibody - ab5914 from Abcam

Prices $380.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
ab5914 (2.5 µg/ml) staining NET1 in Human Tonsil by IHC-P.  Steamed antigen retrieval with citrate buffer pH 6, AP-staining.  This image shows staining of fibrous structures.

Anti-NET1 antibody - ab113202 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab113202 staining NET1 in PC-12 cells treated with milnacipran hydrochloride (ab120755), by ICC/IF. Decrease of NET1 expression correlates with increased concentration of milnacipran hydrochloride, as described in literature.The NGF treated cells were incubated at 37°C for 6 hour in media containing different concentrations of ab120755 (milnacipran hydrochloride ) in DMSO, fixed with 4% formaldehyde for 10 minutes at room temperature and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab113202 (5 μg/ml) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 anti-rabbit polyclonal antibody (ab96899) at 1/250 dilution was used as the secondary antibody. Nuclei were counterstained with DAPI and are shown in blue.

Anti-NET1 antibody [2633C5a] - ab51351 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2633C5a
Anti-NET1 antibody [2633C5a] (ab51351) + Recombinant NET1

Anti-NET1 antibody - C-terminal - ab140879 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis of Formalin fixed and Paraffin Embedded Human placenta tissue labelling NET1 with ab140879 at 9 µg/ml.

Anti-NET1 Antibody (aa509-525) - LS-C3275 from LifeSpan Bioscience

Prices $265.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-NET1 Antibody - LS-C73332 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-NET1 Antibody (clone 2633C5a) - LS-C184452 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2633C5a

Anti-NET1 Antibody (aa356-385, Azide-free, HRP) - LS-C223446 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NET1 Antibody (aa356-385, PE) - LS-C223447 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NET1 Antibody (aa356-385, AP) - LS-C226915 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NET1 Antibody (aa356-385, APC) - LS-C226916 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NET1 Antibody (aa356-385, Biotin) - LS-C226917 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NET1 Antibody - LS-C195144 from LifeSpan Bioscience

Prices $620.00
Sizes 1 ml
Host Chicken
Clonality Polyclonal
Immunofluorescent staining of Netrin 1 antibody. Dissociated cell cultures of an e13 mouse brain showing Netrin-1 (green staining) in neuronal precursor cells.

Anti-NET1 Antibody (aa356-385, FITC) - LS-C226919 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NET1 Antibody (aa546-596) - LS-C289839 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NET1 Antibody - LS-C318233 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-NET1 Antibody - LS-C192475 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of NET1 pAb in extracts from Jurkat and 293T cells.

Anti-NET1 Antibody (HRP) - LS-C318235 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-NET1 Antibody (FITC) - LS-C318239 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-NET1 Antibody (Biotin) - LS-C318238 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-NET1 Antibody (aa231-261) - LS-C323297 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NET1 Antibody (aa72-121) - LS-C102411 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
NET1 antibody LS-C102411 Western blot of 293T cell lysate.
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