CHTOP

Gene Symbol	CHTOP
Entrez Gene	26097
Alt Symbol	C1orf77, FL-SRAG, FOP, SRAG, SRAG-3, SRAG-5, pp7704
Species	Human
Gene Type	protein-coding
Description	chromatin target of PRMT1
Other Description	chromatin target of PRMT1 protein\|friend of PRMT1 protein\|small protein rich in arginine and glycine
Swissprots	D3DV55 Q9H2L0 Q6NSM4 Q5T7Y9 Q9Y3Y2 Q8WYT9 Q9BUC5 Q0VAQ8 Q9H034 Q5T7Y8 Q5T7Z0 Q6PB28 Q2VPI9
Accessions	EAW53290 EAW53291 EAW53292 EAW53293 EAW53294 EAW53295 Q9Y3Y2 AF261137 AAG44673 AF318362 AAL55869 AI929184 AK095230 AK097870 AK308713 AK309844 AL050260 CAB43362 AL512704 CAC21650 BC002733 AAH02733 BC059949 AAH59949 BC070027 AAH70027 BC108721 AAI08722 BC120961 AAI20962 BC120962 AAI20963 BP375397 DC387712 XM_005245085 XP_005245142 XM_005245086 XP_005245143 NM_001206612 NP_001193541 NM_001244664 NP_001231593 NM_015607 NP_056422
Function	Plays an important role in the ligand-dependent activation of estrogen receptor target genes. May play a role in the silencing of fetal globin genes. Recruits the 5FMC complex to ZNF148, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
Subcellular Location	Nucleus. Nucleus, nucleolus. Nucleus, nucleoplasm {ECO:0000250}. Nucleus speckle. Note=Mostly associated with facultative heterochromatin (By similarity). Localizes to regions surrounding nuclear speckles known as perispeckles in which TREX complex assembly seems to occur. {ECO:0000250}.
Tissue Specificity	Expressed in an erythroid progenitor cell line derived from peripheral blood. {ECO:0000269\|PubMed:20688955}.

C1orf77 (C-13) - sc-139230 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

C1orf77 (C-13): sc-139230. Western blot analysis of C1orf77 expression in HeLa whole cell lysate.

C1orf77 (S-12) - sc-139232 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Anti-C1orf77 antibody - ab102993 from Abcam

Prices	$359.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-C1orf77 antibody (ab102993) at 1/100 dilution + 293 cell line lysate at 35 µg

Anti-CHTOP / FOP Antibody (N-Terminus) - LS-C123582 from LifeSpan Bioscience

Prices	$405.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Anti-CHTOP / FOP Antibody (C-Terminus) - LS-C123583 from LifeSpan Bioscience

Prices	$405.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Anti-CHTOP / FOP Antibody (N-Terminus, clone KT59) - LS-C193506 from LifeSpan Bioscience

Prices	$355.00
Sizes	100 µg
Host	Rat
Clonality	Monoclonal
Clone	KT59

Anti-CHTOP / FOP Antibody (aa71-120) - LS-C116607 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

CHTOP / C1orf77 antibody LS-C116607 Western blot of THP-1 cell lysate.

Anti-CHTOP / FOP Antibody (aa198-248) - LS-C290091 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Detection of Human SRAG by Western Blot. Samples: Whole cell lysate from Jurkat (15 and 50 ug), 293T (T; 50 ug) and HeLa (H; 50 ug) cells. Antibody: Affinity purified rabbit anti-SRAG antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Anti-CHTOP / FOP Antibody (aa1-50) - LS-C290088 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CHTOP / FOP Antibody (C-Terminus, clone KT64) IHC-plus™ - LS-B11259 from LifeSpan Bioscience

Prices	$395.00
Sizes	50 µg
Host	Rat
Clonality	Monoclonal
Clone	KT64

Anti-CHTOP / FOP antibody IHC staining of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11259 concentration 10 ug/ml.

CHTOP Antibody - NBP1-88085 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: CHTOP Antibody [NBP1-88085] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

C1orf77 Polyclonal Antibody - bs-15076R from Bioss

Prices	$269.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

C1orf77 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-15076R-A350 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

C1orf77 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-15076R-A488 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

C1orf77 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-15076R-A555 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

C1orf77 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-15076R-A647 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

C1orf77 Polyclonal Antibody, Cy3 Conjugated - bs-15076R-Cy3 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

C1orf77 Polyclonal Antibody, Cy5 Conjugated - bs-15076R-Cy5 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

C1orf77 Polyclonal Antibody, Cy5.5 Conjugated - bs-15076R-Cy5.5 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

C1orf77 Polyclonal Antibody, Cy7 Conjugated - bs-15076R-Cy7 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

C1orf77 Polyclonal Antibody, FITC Conjugated - bs-15076R-FITC from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

C1orf77 Polyclonal Antibody, Biotin Conjugated - bs-15076R-Biotin from Bioss

Prices	$349.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

C1orf77 Polyclonal Antibody, HRP Conjugated - bs-15076R-HRP from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CHTOP antibody produced in rabbit - HPA028647 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-C1ORF77: <B>Cat. No. HPA028647</B>: Immunohistochemical staining of human rectum shows strong nuclear positivity in glandular cells.

Anti-C1ORF77 antibody produced in rabbit - SAB2105968 from Sigma-Aldrich

Prices	$347.50, $347.50
Sizes	50 µg, 100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-C1ORF77: <B>Cat. No. SAB2105968</B>: C1orf77 in THP-1 cell lysates with C1orf77 antibody at 1.0 μg/mL.

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