CHTOP

Gene Symbol	CHTOP
Entrez Gene	26097
Alt Symbol	C1orf77, FL-SRAG, FOP, SRAG, SRAG-3, SRAG-5, pp7704
Species	Human
Gene Type	protein-coding
Description	chromatin target of PRMT1
Other Description	chromatin target of PRMT1 protein|friend of PRMT1 protein|small protein rich in arginine and glycine
Swissprots	D3DV55 Q9H2L0 Q6NSM4 Q5T7Y9 Q9Y3Y2 Q8WYT9 Q9BUC5 Q0VAQ8 Q9H034 Q5T7Y8 Q5T7Z0 Q6PB28 Q2VPI9
Accessions	EAW53290 EAW53291 EAW53292 EAW53293 EAW53294 EAW53295 Q9Y3Y2 AF261137 AAG44673 AF318362 AAL55869 AI929184 AK095230 AK097870 AK308713 AK309844 AL050260 CAB43362 AL512704 CAC21650 BC002733 AAH02733 BC059949 AAH59949 BC070027 AAH70027 BC108721 AAI08722 BC120961 AAI20962 BC120962 AAI20963 BP375397 DC387712 XM_005245085 XP_005245142 XM_005245086 XP_005245143 NM_001206612 NP_001193541 NM_001244664 NP_001231593 NM_015607 NP_056422
Function	Plays an important role in the ligand-dependent activation of estrogen receptor target genes. May play a role in the silencing of fetal globin genes. Recruits the 5FMC complex to ZNF148, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
Subcellular Location	Nucleus. Nucleus, nucleolus. Nucleus, nucleoplasm {ECO:0000250}. Nucleus speckle. Note=Mostly associated with facultative heterochromatin (By similarity). Localizes to regions surrounding nuclear speckles known as perispeckles in which TREX complex assembly seems to occur. {ECO:0000250}.
Tissue Specificity	Expressed in an erythroid progenitor cell line derived from peripheral blood. {ECO:0000269|PubMed:20688955}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human C1orf77 full length protein - ab161896 from Abcam Category Protein Prices $402.00 Sizes 2 µg Source Wheat germ Species Human

CHTOP / FOP Antibody Blocking Peptide - LS-E19971 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CHTOP Protein - H00026097-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

C1orf77-Antibody-N-term-Blocking-Peptide - BP9658a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

C1orf77 Blocking Peptide - 33R-5099 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

C1orf77 - H00026097-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

C1orf77 fusion protein - ag14736 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human Chromatin target of PRMT1 protein(CHTOP) - CSB-YP897109HU CSB-EP897109HU CSB-BP897109HU CSB-MP897109HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

C1orf77 - TP311107 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant Human CHTOP protein, MYC/DDK-tagged - CHTOP-01H from Creative Biomart Category Protein Source HEK293 Species Human

CHTOP Recombinant Protein Antigen - NBP1-88085PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

CHTOP Peptide, Human - M34GP03163H from Creative Peptides Category Peptide Source Synthetic. Species Human

C1orf77 fusion protein - Ag26580 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

CHTOP Recombinant Protein Antigen - NBP2-55155PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

Chromatin target of PRMT1 protein (CHTOP), Recombinant Protein - MBS1332242 from MyBioSource Category Protein Prices $995.00, $995.00, $1,225.00, $1,225.00, $1,525.00, $1,525.00, $1,990.00, $1,990.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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