Gene Symbol | SOSTDC1 |
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Entrez Gene | 25928 |
Alt Symbol | CDA019, ECTODIN, USAG1 |
Species | Human |
Gene Type | protein-coding |
Description | sclerostin domain containing 1 |
Other Description | cystine-knot containing secreted protein|ectodermal BMP inhibitor|sclerostin domain-containing protein 1|uterine sensitization-associated protein-1 |
Swissprots | Q6X4U4 Q9Y3U3 Q96HJ7 A8MUA6 |
Accessions | AAQ96855 EAL24287 EAW93669 Q6X4U4 AB059270 BAC20331 AF361494 AAL57219 AI540640 AI927000 AK093408 BAG52710 AK315682 BAG38047 AL050024 CAB43243 AY255634 AAQ83296 BC008484 AAH08484 HQ448027 ADQ32508 NM_015464 NP_056279 |
Function | May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction Enhances Wnt signaling and inhibits TGF-beta signaling (By similarity). Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner. {ECO:0000250, ECO:0000269|PubMed:15020244}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:15020244}. |
Tissue Specificity | Highly expressed in kidney and weakly in lung. {ECO:0000269|PubMed:15020244}. |
SOSTDC1 CRISPR/Cas9 KO Plasmid (h) - sc-403398 from Santa Cruz Biotechnology
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SOSTDC1 HDR Plasmid (h) - sc-403398-HDR from Santa Cruz Biotechnology
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SOSTDC1 Double Nickase Plasmid (h) - sc-403398-NIC from Santa Cruz Biotechnology
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SOSTDC1 Double Nickase Plasmid (h2) - sc-403398-NIC-2 from Santa Cruz Biotechnology
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SOSTDC1 CRISPR Activation Plasmid (h) - sc-403398-ACT from Santa Cruz Biotechnology
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SOSTDC1 CRISPR Activation Plasmid (h2) - sc-403398-ACT-2 from Santa Cruz Biotechnology
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SOSTDC1 Lentiviral Activation Particles (h) - sc-403398-LAC from Santa Cruz Biotechnology
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SOSTDC1 Lentiviral Activation Particles (h2) - sc-403398-LAC-2 from Santa Cruz Biotechnology
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SOSTDC1 siRNA (h) - sc-89697 from Santa Cruz Biotechnology
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SOSTDC1 shRNA Plasmid (h) - sc-89697-SH from Santa Cruz Biotechnology
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SOSTDC1 shRNA (h) Lentiviral Particles - sc-89697-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN20345 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20345 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08347 from Sigma-Aldrich
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SOSTDC1 siRNA (Human) - CRH8595 from Cohesion Biosciences
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SOSTDC1 - MBS8235884 from MyBioSource
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shRNA set against Human SOSTDC1 (NM_015464.2) - SHH415244 from Creative biogene
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shRNA set against Human SOSTDC1(NM_015464.2) - SHL016950 from Creative biogene
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Human SOSTDC1 siRNA - orb269097 from Biorbyt
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SOSTDC1 shRNA Plasmid (Human) - CHH8595 from Cohesion Biosciences
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SOSTDC1 miRNA 3'UTR clone - MiUTR1H-09757 from Creative biogene
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